Evidence map›Paper›PMID 38524118›Full record

ArticleFrontiers in aging neuroscience2024

Physical exercise frequency and cognition: a multicenter cross-sectional cohort study.

Chen Wen, Jing-Huan Gan, Guo-Wei Huang, Xiao-Dan Wang, Yang Lü, Jian-Ping Niu, Xin-Ling Meng, Pan Cai, Yang Li, Bao-Zhi Gang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Chen Wen *Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Beijing, China.
Jing-Huan Gan *Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Guo-Wei HuangDepartment of Nutrition and Food Science, Tianjin Key Laboratory of Environment, Nutrition and Public Health, School of Public Health, Tianjin Medical University, Tianjin, China.
Xiao-Dan WangDepartment of Neurology, Tianjin Huanhu Hospital, Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Dementia Institute, Tianjin, China.
Yang LüDepartment of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jian-Ping NiuDepartment of Neurology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, China.
Xin-Ling MengDepartment of Neurology, Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University, Urumqi, China.
Pan CaiDementia Clinic, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Yang LiDepartment of Neurology, The First Hospital of Shanxi Medical University, Taiyuan, China.
Bao-Zhi GangDepartment of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yong YouDepartment of Neurology, Second Affiliated Hospital of Hainan Medical University, Haikou, China.
Yan LvDepartment of Neurology, Hainan General Hospital, Haikou, China.
Zhi-Hong RenDepartment of Neurology, Beijing Electric Power Hospital, State Grid Corporation of China, Capital Medical University, Beijing, China.
Shuai LiuDepartment of Neurology, Tianjin Huanhu Hospital, Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Dementia Institute, Tianjin, China.
Yan ZengBrain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.
Yong JiDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Dementia imposes a heavy burden on society and families, therefore, effective drug treatments, exploring and preventing factors associated with dementia, are paramount. To provide reference points for the best frequency of physical exercise (physical exercise), we investigated the association between frequency of PE and cognition in Chinese old adults. Methods: 16,181 Chinese participants aged 65 years or older were included in this study. Associations between PE and cognition were estimated multivariate logistic and linear regression analyses. Associations were further investigated across dementia subtypes (Alzheimer dementia, vascular dementia, and other types of dementia). Subgroup analyses were performed in different age groups, in populations with and without stroke, and those with and without hypertension. Results: PE associated with dementia after adjusting for full covariates (OR: 0.5414, 95% CI: 0.4536-0.6491, Conclusion: The best exercise frequency is exercising ≥3 times/week for individuals from different dementia subtypes and age groups. While for those without hypertension, PE at 1-2 times /week is also beneficial.

Indexed as

Alzheimer’s diseasecognitive impairmentdementiahealthy guidancephysical exercise frequency

Identifiers

PMID38524118
PMCPMC10958531

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.