Evidence map›Paper›PMID 38523904›Full record

ArticleProstate international2024

Infectious complications of transrectal prostate biopsy in patients receiving targeted antibiotic prophylaxis after urethral and rectal swab versus standard prophylaxis: A prospective comparative study.

Sotirios Gatsos, Nikolaos Kalogeras, Georgios Dimakopoulos, Michael Samarinas, Anna Papakonstantinou, Efi Petinaki, Vassilios Tzortzis, Stavros Gravas

Open access · goldAbstract read
In one paragraph

Article in Prostate international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Sotirios GatsosDepartment of Urology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Nikolaos KalogerasDepartment of Urology, Agios Dimitrios General Hospital, Thessaloniki, Greece.
Georgios DimakopoulosBIOSTATS, Epirus Science and Technology Park, Campus of the University of Ioannina, Ioannina, Greece.
Michael SamarinasDepartment of Urology, Koutlibanio General Hospital, Larisa, Greece.
Anna PapakonstantinouDepartment of Urology, Agios Dimitrios General Hospital, Thessaloniki, Greece.
Efi PetinakiDepartment of Microbiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Vassilios TzortzisDepartment of Urology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Stavros GravasMedical School, University of Cyprus, Nicosia, Cyprus.
University of Thessaly · GRAgios Pavlos General Hospital · GR404 General Military Hospital · GRUniversity of Cyprus · CYUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To evaluate the role of targeted antibiotic prophylaxis (TAP) after rectal and urethral swab cultures compared to empiric antibiotic prophylaxis (EAP) for the prevention of infectious complications after transrectal ultrasound-guided prostate biopsy (TRUS-Bx). Methods: We conducted a prospective comparative study on 141 patients who underwent TRUS-Bx and were allocated in two groups. The first group (n = 71) received EAP with ciprofloxacin and the second (n = 70) received TAP according to rectal and urethral cultures. Post-biopsy infectious complications rates were compared between the two groups. Fluoroquinolone resistance (FQ-R) in the urethral and rectal swabs was recorded. Baseline characteristics were analyzed to assess their relationship with infectious complications and antibiotic resistance. Results: A total of 8 infectious complications were observed, 7 of them in the EAP group (9.85%) and 1 in the TAP group (1.4%). There was a statistically significant difference in febrile UTIs between the two groups (6 vs 0, Conclusion: Combination of rectal and urethral swab cultures for TAP was able to detect FQ-R bacteria carriers and was associated with fewer infectious complications compared to EAP.

Indexed as

Anti-bacterial agentsBiopsyProstateUrinary tract infections

Identifiers

PMID38523904
PMCPMC10960084
OpenAlexW4388947326

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.