ReviewProstate international2024
Shifting to transperineal prostate biopsy: A narrative review.
Review in Prostate international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Erectile dysfunction following prostate biopsy: a comparative analysis of transrectal versus transperineal approaches.International urology and nephrology · 2026Pooled it
- Comparison of Urinary Tract Infection Rates Between Transperineal Prostate Biopsies with and Without Prophylactic Antibiotics: An Updated Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Infectious complications after transrectal prostate biopsy in Algeria: A prospective study in a high-resistance setting.Prostate international · 2026Article
- Infection risks and biopsy-associated complications in prostate cancer diagnosis: a review of recent literatures.Prostate cancer and prostatic diseases · 2026Review
- Effect of Anesthesia Type on Clinically Significant Prostate Cancer Detection in Transperineal MRI-Targeted Biopsy.Cancers · 2026Article
- Transperineal versus transrectal magnetic resonance imaging-fusion ultrasound-guided prostate biopsy: a comparative analysis of cancer detection in patients with prior negative transrectal ultrasound scan biopsy.Prostate international · 2026Article
- Freehand transperineal prostate biopsy under local anesthesia using a novel needle guide system with angle-adjustment feature.The Canadian journal of urology · 2025Article
- Article
- Infectious complications in patients undergoing transrectal prostate-biopsy with ciprofloxacin compared to fosfomycin-trometamol.World journal of urology · 2025Article
- Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience.Investigative and clinical urology · 2025Article
- Use versus nonuse of antimicrobial prophylaxis prior to transperineal prostate biopsy: a propensity score-matched analysis.Prostate international · 2025Article
- The addition of peri-operative gentamicin with ciprofloxacin reduces infection and sepsis rates post transrectal prostate biopsy.Prostate international · 2025Article
- Changes in the prostate biopsy landscape-how can we improve quality?Translational andrology and urology · 2025Article
- Carbon footprints in the urologic field: From diagnosis to surgery.Investigative and clinical urology · 2025Review
- Single-dose vs prolonged antibiotic prophylaxis of fosfomycin for transrectal prostate biopsy: a single-center prospective, randomized, controlled trial.Prostate international · 2025Article
- CT-guided transperineal biopsy for prostate cancer in the absence of rectal access.Radiology case reports · 2024Article
- Effects of bladder neck sparing on continence outcomes of robotic-assisted radical prostatectomy: a systemic review and metaanalysis.Prostate international · 2024Review
- Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy.Current urology reports · 2024Review
- Incidence of Infection Following Local Anesthetic Transperineal Prostate Biopsy: A Single-Centre Experience.Cureus · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To address the limitations and challenges associated with transrectal (TR) biopsy and to present transperineal (TP) biopsy as a viable and potentially safer alternative to TR biopsy. Prostate cancer (PCa) is a significant global health concern. The prevalence of advanced-stage prostate cancer in Asia is higher than that in the United States, emphasizing the need for effective screening and diagnosis methods. The gold standard of diagnosis is a TR biopsy. However, it has limitations due to the risk of infection and potential complications, such as injury to the rectal artery. Efforts have been made to address issues such as false-negative biopsies, under-sampling, and over-sampling through MRI-guided biopsies. However, the TR approach makes it difficult to access the apical and anterior regions of the prostate. TP biopsy has emerged as an alternative to address the limitations of TR biopsy. Nevertheless, a TP biopsy is a painful procedure, requiring the use of general anesthesia and expensive equipment. As a result, it has been perceived as costly and time-consuming. In addition, it requires a steep learning curve. The introduction of local anesthesia such as pudendal nerve block and the adoption of freehand techniques have contributed to the feasibility of performing TP biopsy. Recent research indicates that freehand TP biopsy can yield comparable diagnostic results to template-guided approaches. The diagnostic performance, cancer detection rates, and complication rates of TP biopsy have demonstrated its potential as a safe and effective diagnostic method.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.