Evidence map›Paper›PMID 38523771›Full record

ArticleNature photonics2023

Label-free biomedical optical imaging.

Natan T Shaked, Stephen A Boppart, Lihong V Wang, Jürgen Popp

Abstract read
In one paragraph

Article in Nature photonics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Detecting drug-induced nephrotoxicity using simultaneous label-free autofluorescence multiharmonic microscopy.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Natan T ShakedDepartment of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel.
Stephen A BoppartBeckman Institute for Advanced Science and Technology, Department of Electrical and Computer Engineering,; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Lihong V WangCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA, USA.
Jürgen PoppLeibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research, Jena, Germany; Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany.

Funding

The Center for Label-free Imagingand Multiscale Biophotonics (CLIMB)P41EB031772 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Stephen A Boppart · 2022 to 2026
$7.6M
Massively parallel high-speed 3D functional photoacoustic computed tomography of the adult human brainU01EB029823 · NIBIB · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI WANG, DANNY JJ, WANG, LIHONG · 2020 to 2024
$6.7M
High-speed panoramic 3D photoacoustic computed tomography of the breastR35CA220436 · NCI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI WANG, LIHONG · 2018 to 2024
$6.4M
Safe, rapid & functional pediatric brain imaging using photoacoustic computed tomographyR01NS102213 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANASTASIO, MARK A, WANG, LIHONG · 2017 to 2021
$3.0M
Label-free intraoperative photoacoustic microscopy for rapid diagnosis of tissue biopsies with specimen integrityR01EB028277 · NIBIB · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI D'APUZZO, MASSIMO, WANG, LIHONG · 2019 to 2022
$2.6M
Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor MarginsR01CA213149 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2017 to 2021
$2.4M
Imaging tumor microenvironment by Optical Fiber-Tethered Simultaneous Lifetime-resolved Autofluorescence-Multiharmonic (OFT-SLAM) microscopyR01CA241618 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A, TU, HAOHUA · 2019 to 2022
$1.6M
NCI NIH HHS R01 CA213149NCI NIH HHS R01 CA241618NCI NIH HHS R35 CA220436NIBIB NIH HHS P41 EB031772NIBIB NIH HHS R01 EB028277NIBIB NIH HHS U01 EB029823NINDS NIH HHS R01 NS102213
6 · The paper itself

Abstract

Label-free optical imaging employs natural and nondestructive approaches for the visualisation of biomedical samples for both biological assays and clinical diagnosis. Currently, this field revolves around multiple broad technology-oriented communities, each with a specific focus on a particular modality despite the existence of shared challenges and applications. As a result, biologists or clinical researchers who require label-free imaging are often not aware of the most appropriate modality to use. This manuscript presents a comprehensive review of and comparison among different label-free imaging modalities and discusses common challenges and applications. We expect this review to facilitate collaborative interactions between imaging communities, push the field forward and foster technological advancements, biophysical discoveries, as well as clinical detection, diagnosis, and monitoring of disease.

Identifiers

PMID38523771
PMCPMC10956740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.