Evidence map›Paper›PMID 38523575›Full record

ArticleMagnetic resonance in medicine2024

MR elastography-based slip interface imaging (SII) for functional assessment of myofascial interfaces: A feasibility study.

Emi Hojo, Yi Sui, Xiang Shan, Keni Zheng, Phillip Rossman, Armando Manduca, Garret M Powell, Kai-Nan An, Kristin D Zhao, Brent A Bauer and 2 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Emi HojoDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.ORCID 0000-0002-4229-0435
Yi SuiDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.ORCID 0000-0002-8177-1661
Xiang ShanDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Keni ZhengDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Phillip RossmanDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Armando ManducaDepartment of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.ORCID 0000-0002-9411-5671
Garret M PowellDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Kai-Nan AnOrthopedics Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Kristin D ZhaoPhysical Medicine and Rehabilitation, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Brent A BauerGeneral Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Richard L EhmanDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.ORCID 0000-0001-7041-5074
Ziying YinDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.ORCID 0000-0003-3235-966X

Funding

Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
MR elastography-based detection of impaired decoupling performance of the pia-arachnoid complex (PAC) associated with repetitive head impactsR01NS113760 · NINDS · MAYO CLINIC ROCHESTER · PI Ziying Yin · 2019 to 2026
$2.9M
MRI-based quantitative characterization of impaired myofascial interface properties in myofascial pain syndromeR61AT012185 · NCCIH · MAYO CLINIC ROCHESTER · PI BAUER, BRENT A, YIN, ZIYING · 2022 to 2022
$2.0M
MRI-based quantitative characterization of impaired myofascial interface properties in myofascial pain syndromeR33AT012185 · NCCIH · MAYO CLINIC ROCHESTER · PI BAUER, BRENT A, YIN, ZIYING · 2025 to 2025
$1.6M
Electroacupuncture for Major Depression: A Pilot StudyR21AT001218 · NCCIH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MULSANT, BENOIT H · 2003 to 2004
$372k
NCCIH NIH HHS R21 AT001218NCCIH NIH HHS R33 AT012185NCCIH NIH HHS R61 AT012185NCCIH NIH HHS R61AT012185NIBIB NIH HHS R37 EB001981NINDS NIH HHS R01 NS113760
6 · The paper itself

Abstract

purposeAbnormal adherence at functional myofascial interfaces is hypothesized as an important phenomenon in myofascial pain syndrome. This study aimed to investigate the feasibility of MR elastography (MRE)-based slip interface imaging (SII) to visualize and assess myofascial mobility in healthy volunteers.

methodsSII was used to assess local shear strain at functional myofascial interfaces in the flexor digitorum profundus (FDP) and thighs. In the FDP, MRE was performed at 90 Hz vibration to each index, middle, ring, and little finger. Two thigh MRE scans were performed at 40 Hz with knees flexed and extended. The normalized octahedral shear strain (NOSS) maps were calculated to visualize myofascial slip interfaces. The entropy of the probability distribution of the gradient NOSS was computed for the two knee positions at the intermuscular interface between vastus lateralis and vastus intermedius, around rectus femoris, and between vastus intermedius and vastus medialis.

resultsNOSS map depicted distinct functional slip interfaces in the FDP for each finger. Compared to knee flexion, clearer slip interfaces and larger gradient NOSS entropy at the vastus lateralis-vastus intermedius interface were observed during knee extension, where the quadriceps are not passively stretched. This suggests the optimal position for using SII to visualize myofascial slip interface in skeletal muscles is when muscles are not subjected to any additional force.

conclusionThe study demonstrated that MRE-based SII can visualize and assess myofascial interface mobility in extremities. The results provide a foundation for investigating the hypothesis that myofascial pain syndrome is characterized by changes in the mobility of myofascial interfaces.

Indexed as

Elasticity Imaging TechniquesFeasibility StudiesAdultFemaleHealthy VolunteersHumansMagnetic Resonance ImagingMaleMuscle, SkeletalMyofascial Pain SyndromesThighYoung Adultfunctional interfaceMREmusclemyofascial mobilitymyofascial tissueslip interface imaging

Identifiers

PMID38523575
PMCPMC11142878

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.