Evidence map›Paper›PMID 38523465›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2024

Prediction of cardiovascular and renal risk among patients with apparent treatment-resistant hypertension in the United States using machine learning methods.

George Bakris, Pei Paul Lin, Chang Xu, Cindy Chen, Veronica Ashton, Mukul Singhal

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

George BakrisUniversity of Chicago Medicine, Chicago, Illinois, USA.ORCID 0000-0003-1183-1267
Pei Paul LinJanssen Scientific Affairs, LLC, Titusville, New Jersey, USA.
Chang XuJanssen Scientific Affairs, LLC, Titusville, New Jersey, USA.
Cindy ChenJanssen Scientific Affairs, LLC, Titusville, New Jersey, USA.
Veronica AshtonJanssen Scientific Affairs, LLC, Titusville, New Jersey, USA.ORCID 0000-0003-4880-1897
Mukul SinghalJanssen Scientific Affairs, LLC, Titusville, New Jersey, USA.
Janssen (United States) · USUniversity of Chicago · US

Funding

Janssen Scientific Affairs, LLC
6 · The paper itself

Abstract

Apparent treatment-resistant hypertension (aTRH), defined as blood pressure (BP) that remains uncontrolled despite unconfirmed concurrent treatment with three antihypertensives, is associated with an increased risk of developing cardiovascular and renal complications compared with controlled hypertension. We aimed to identify the characteristics of aTRH patients with an elevated risk of major adverse cardiovascular events plus (MACE+; defined as stroke, myocardial infarction, or heart failure hospitalization) and end stage renal disease (ESRD). This retrospective cohort study included aTRH patients (BP ≥140/90 mmHg and taking ≥3 antihypertensives) from the United States-based Optum

Indexed as

Antihypertensive AgentsHypertensionKidney Failure, ChronicMachine LearningAdultAgedBlood PressureCardiovascular DiseasesFemaleHeart FailureHumansMaleMiddle AgedMyocardial InfarctionRetrospective StudiesRisk AssessmentAntihypertensive Agentselectronic health recordsend stage renal diseasemajor adverse cardiovascular eventsresistant hypertensionrisk factors

Identifiers

PMID38523465
PMCPMC11088433
OpenAlexW4393155093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.