ReviewJournal of medical case reports2024
Squamous cell carcinoma malignant transformation in mature cystic teratoma of the ovary: a case report and review of the literature.
Review in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Squamous Cell Carcinoma Arising From Mature Cystic Teratoma in a 39-Year-Old Woman: A Case Report.Cureus · 2026Article
- A Large Mature Teratoma in a Postmenopausal Women.Case reports in obstetrics and gynecology · 2026Article
- Frequency and clinicopathological features of somatic neoplasms arising in ovarian mature teratomas: a single-center experience.Pathology oncology research : POR · 2026Article
- Establishment and characterization of preclinical model of primary ovarian squamous cell carcinoma.Human cell · 2025Article
- When Teratomas Turn Brutal: From Indolent to Invasive in Stage IIIB Ovarian Squamous Cell Carcinoma.Cureus · 2025Article
- Squamous cell carcinoma arising from mature cystic teratoma of the ovary in a premenopausal women: A rare case report.International journal of surgery case reports · 2025Article
- Squamous Cell Carcinoma of the Ovary: A Rare Case.Cureus · 2024Article
- Mucinous cystadenoma and carcinoid tumor arising from an ovarian mature cystic teratoma in a 60 year-old patient: a case report.Journal of medical case reports · 2024Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMature cystic teratoma of the ovary is classified among the benign ovarian germ cell neoplasms, and its malignant transformation occurs very rarely (in about 2%). As a result of nonspecific signs and symptoms, preoperative diagnosis of theses malignancies is a challenge to clinicians, resulting in delayed diagnosis (in advanced stages) and poor outcomes. CASE PRESENTATION: We report the case of a 43-year-old Iranian woman with progressive distension of the abdomen and hypogastric pain, who was diagnosed with squamous cell carcinoma transformation in a mature cystic teratoma of the ovary confirmed by histopathology examination. Total abdominal hysterectomy, bilateral salpingooophorectomy, and comprehensive staging surgery were performed for the patient, and she was scheduled for chemotherapy after the surgery. She responded well to the treatment and is currently continuing her chemotherapy process.
conclusionThere are a great number of reports in the literature regarding mature cystic teratoma of the ovary transformation into malignancy, so these neoplasms must be considered as a possible differential diagnosis and should be evaluated in older individuals with abdominal pain and palpable mass, or those with considerable tumor diameter and raised serum tumor markers.
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