Evidence map›Paper›PMID 38523189›Full record

ArticleScientific reports2024

Antibacterial and hemocompatibility potentials of nano-gold-cored alginate preparation against anaerobic bacteria from acne vulgaris.

Hanan A Abbas, Ali A Taha, Ghassan M Sulaiman, Amer Al Ali, Humood Al Shmrany, Haralambos Stamatis, Hamdoon A Mohammed, Riaz A Khan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Empyema Caused byInfection and drug resistance · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Hanan A AbbasDivision of Biotechnology, Department of Applied Sciences, University of Technology, Baghdad, Iraq.
Ali A TahaDivision of Biotechnology, Department of Applied Sciences, University of Technology, Baghdad, Iraq.
Ghassan M SulaimanDivision of Biotechnology, Department of Applied Sciences, University of Technology, Baghdad, Iraq. ghassan.m.sulaiman@uotechnology.edu.iq.
Amer Al AliDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, 255, 67714, Bisha, Saudi Arabia.
Humood Al ShmranyDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, 11942, Alkharj, Saudi Arabia.
Haralambos StamatisDepartment of Biological Applications and Technology, University of Ioannina, Ioannina, Greece.
Hamdoon A MohammedDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, 51452, Qassim, Saudi Arabia.
Riaz A KhanDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, 51452, Qassim, Saudi Arabia.
University of Technology - Iraq · IQQassim University · SAPrince Sattam Bin Abdulaziz University · SAUniversity of Bisha · SAUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne is a prevalent dermatological disease, with high global incidence, and is a health menace. The current study aimed to isolate and characterize the anaerobic bacteria responsible for the condition. Causes of a total of 70 acne-based bacterium isolates obtained from patients of mild, moderate, and severe acne, 24 were Clostridium innocuum, 21 were Lactobacillus plantarum, 13 were Anaerococcus prevotii, and 12 were Peptoniphilus asaccharolyticus. Nearly 69% of males were suffering, while the rest were females at 31%. The 15-30 years old age group was the most affected. The gold/alginate nanoparticles' nanopreparation (GANPs) produced from chloroauric acid and sodium alginate was an effective treatment against the acne conditions under the experimental conditions. The nanopreparation exhibited significant inhibitory activity against anaerobic bacterial isolates, with a minimum inhibitory concentration of 200 µg/ml for A. prevotii and P. asaccharolyticus, and 400 µg/ml for C. innocuum and L. plantarum. The in vitro efficacy of the GANPs on human blood parameters was also assessed. The concurrent results suggested potential antibacterial activity and hemocompatibility of the product, which has promise to be used as a successful antibacterial agent for acne.

Indexed as

Acne VulgarisBacteria, AnaerobicAdolescentAdultAlginatesAnti-Bacterial AgentsFemaleHumansMaleMicrobial Sensitivity TestsYoung AdultAlginatesAnti-Bacterial AgentsAcneAnaerobic bacteriaAnaerococcus prevotiiBiocompatibilityClostridium innocuumGold/alginate nanopreparationHemocompatibilityLactobacillus plantarumNanoparticlesPeptoniphilus asaccharolyticus

Identifiers

PMID38523189
PMCPMC10961324
OpenAlexW4393131254

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.