Evidence map›Paper›PMID 38522645›Full record

ArticleJournal of molecular biology2024

NNDB: An Expanded Database of Nearest Neighbor Parameters for Predicting Stability of Nucleic Acid Secondary Structures.

Abhinav Mittal, Douglas H Turner, David H Mathews

Abstract read
In one paragraph

Article in Journal of molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Markov models of SHAPE data improve secondary structure prediction.bioRxiv : the preprint server for biology · 2026
    Article
  3. Nearest Neighbor Parameters for Estimating RNA Folding Stability withbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abhinav MittalDepartment of Biochemistry & Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for RNA Biology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Douglas H TurnerCenter for RNA Biology, University of Rochester Medical Center, Rochester, NY 14642, USA; Department of Chemistry, University of Rochester, Rochester, NY 14627, USA.
David H MathewsDepartment of Biochemistry & Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for RNA Biology, University of Rochester Medical Center, Rochester, NY 14642, USA. Electronic address: David_Mathews@urmc.rochester.edu.

Funding

RNA Structure Modeling Using Physics and Sequence ComparisonR35GM145283 · NIGMS · UNIVERSITY OF ROCHESTER · PI DAVID H. MATHEWS · 2022 to 2026
$2.7M
NIGMS NIH HHS R35 GM145283
6 · The paper itself

Abstract

Nearest neighbor thermodynamic parameters are widely used for RNA and DNA secondary structure prediction and to model thermodynamic ensembles of secondary structures. The Nearest Neighbor Database (NNDB) is a freely available web resource (https://rna.urmc.rochester.edu/NNDB) that provides the functional forms, parameter values, and example calculations. The NNDB provides the 1999 and 2004 set of RNA folding nearest neighbor parameters. We expanded the database to include a set of DNA parameters and a set of RNA parameters that includes m

Indexed as

DNANucleic Acid ConformationRNAComputational BiologyDatabases, Nucleic AcidThermodynamicsDNARNANearest Neighbor AnalysisNucleic Acid Folding ThermodynamicsRNA Secondary Structure Prediction

Identifiers

PMID38522645
PMCPMC11377154

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.