Evidence map›Paper›PMID 38522176›Full record

ArticleThe International journal on drug policy2024

Acceptability and anticipated effectiveness of a safe supply of opioids, among people who inject opioids in King County, WA.

Adam Palayew, Caleb J Banta-Green, Malika Lamont, Deaunte Damper, Courtney Moreno, Steven M Goodreau, Stephen J Mooney, Sara N Glick

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The International journal on drug policy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Adam PalayewDepartment of Epidemiology, School of Public Health, University of Washington, USA; VOCAL, Washington, USA. Electronic address: apalayew@uw.edu.
Caleb J Banta-GreenDepartment of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, USA; Department of Health Systems and Population Health, School of Public Health, University of Washington, USA.
Malika LamontVOCAL, Washington, USA; Public Defenders Association, Seattle, Washington, USA.
Deaunte DamperVOCAL, Washington, USA.
Courtney MorenoPublic Health Seattle King County, Division of Infectious Diseases, Seattle, Washington, USA.
Steven M GoodreauDepartment of Anthropology, School of Public Health, University of Washington, USA.
Stephen J MooneyDepartment of Epidemiology, School of Public Health, University of Washington, USA.
Sara N GlickDepartment of Epidemiology, School of Public Health, University of Washington, USA; Public Health Seattle King County, Division of Infectious Diseases, Seattle, Washington, USA; Division of Allergy and Infectious Diseases, School of Medicine, University of Washington, USA.
University of Washington · USPublic Health – Seattle & King County · USNational Legal Aid & Defender Association · US

Funding

Scientific/Technical CoreP2CHD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI SARA R. CURRAN · 2017 to 2026
$6.3M
NICHD NIH HHS P2C HD042828
6 · The paper itself

Abstract

backgroundOpioid overdose mortality in the US has exceeded one million deaths over the last two decades. A regulated opioid supply may help prevent future overdose deaths by reducing exposure to the unregulated opioid supply. We examined the acceptability, delivery model preference, and anticipated effectiveness of different regulated opioid models among people in the Seattle area who inject opioids.

methodsWe enrolled people who inject drugs in the 2022 Seattle-area National HIV Behavior Surveillance (NHBS) survey. Participants were recruited between July and December 2022 using respondent-driven sampling. Participants who reported injecting opioids (N = 453) were asked whether regulated opioids would be acceptable, their preferred model of receiving regulated opioids, and the anticipated change in individual overdose risk from accessing a regulated opioid supply.

resultsIn total, 369 (81 %) participants who injected opioids reported that a regulated opioid supply would be acceptable to them. Of the 369 who found a regulated opioid supply to be acceptable, the plurality preferred a take-home model where drugs are prescribed (35 %), followed closely by a dispensary model that required no prescription (28 %), and a prescribed model where drugs need to be consumed on site (13 %), a model where no prescription is required and drugs can be accessed in a community setting with a one-time upfront payment was the least preferred model (5 %). Most participants (69 %) indicated that receiving a regulated opioid supply would be "a lot less risky" than their current supply, 20 % said, "a little less risky", 10 % said no difference, and 1 % said a little or a lot more risky.

conclusionA regulated opioid supply would be acceptable to most participants, and participants reported it would greatly reduce their risk of overdose. As overdose deaths continue to increase in Washington state pragmatic and effective solutions that reduce exposure to unregulated drugs are needed.

Indexed as

Analgesics, OpioidOpioid-Related DisordersSubstance Abuse, IntravenousAdultDrug and Narcotic ControlDrug OverdoseFemaleHumansMaleMiddle AgedOpiate OverdoseWashingtonYoung AdultAnalgesics, OpioidAcceptabilityDrug useFatal overdoseOverdose preventionSafer opioid supply

Identifiers

PMID38522176
PMCPMC11730526
OpenAlexW4393130628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.