ArticleAge and ageing2024
Pain trajectories and their associations with cognition among older adults: a 10-year cohort study from network perspective.
Article in Age and ageing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Dynamic prediction of adverse outcomes in discharged COPD patients using patient-reported outcomes.BMC medical research methodology · 2026Observational
- Beyond pain presence: the impact of multisite pain and pain interference on cognitive functioning among middle-aged and older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Association and attributable hospital costs of chronic pain with relevant geriatric sensitive diseases among the older adults.Frontiers in public health · 2026Article
- Sex-specific trajectories and variability of pain burden in relation to cognitive decline and depressive symptoms in older adults: a prospective cohort study from health and retirement study.BMC public health · 2025Article
- Longitudinal online weekly reports of non-cognitive symptoms and events can differentiate incident mild cognitive impairment from stable cognitively healthy older adults.Journal of Alzheimer's disease : JAD · 2025Article
- Multimodal analgesia in resource-limited settings: A comparative analysis of postoperative pain management strategies in Pakistan.PLOS global public health · 2025Article
- Depressive and Insomnia Symptoms Among Older Adults With Different Chronic Pain Trajectories: A Network Analysis Based on Observation Over an Eight-Year Period.Depression and anxiety · 2025Article
- Association between chronic pain and cognitive frailty among middle-aged and elderly individuals: evidence from the China Health and Retirement Longitudinal Study.Frontiers in aging neuroscience · 2024Article
- Dual group-based trajectories of physical activity and cognitive function in aged over 55: a nationally representative cohort study.Frontiers in public health · 2024Article
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11 authors.
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Abstract
backgroundFew studies have examined the associations between pain trajectories and cognitive function in older adults. This study explored the associations between pain trajectories and different cognitive domains in older adults from a network perspective.
methodsData on pain trajectories were derived from the Health and Retirement Study between 2010 and 2020 using latent class growth analyses. Measurements of key cognition domains, including memory, attention, calculation, orientation and language, were included. Linear regression and network analysis were performed to evaluate the associations between different pain trajectories and cognition.
resultsA total of 9,551 older adults were included in this study and three trajectories of pain were identified. After controlling for the covariates, persistent severe pain trajectory was associated with poorer overall cognition, memory and calculation ability when compared to mild or non-persistent pain trajectory. In the pain and cognition network model, memory (expected influence (EI) = 0.62), language (EI = 0.58) and calculation (EI = 0.41) were the most central domains.
conclusionsPain trajectories appeared stable over time among older adults in this study. Severity of persistent pain was an important risk factor for poor cognition, especially in relation to memory and calculation domains. Interventions targeting memory, language and calculation domains might be useful in addressing cognitive decline in older adults with persistent pain.
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