Evidence map›Paper›PMID 38520704›Full record

ArticleJournal of biomedical materials research. Part B, Applied biomaterials2024

Direct inkjet writing of polylactic acid/β-tricalcium phosphate composites for bone tissue regeneration: A proof-of-concept study.

Vasudev Vivekanand Nayak, Vijayavenkataraman Sanjairaj, Rakesh Kumar Behera, James E Smay, Nikhil Gupta, Paulo G Coelho, Lukasz Witek

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vasudev Vivekanand NayakDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida, USA.ORCID 0000-0003-2739-0339
Vijayavenkataraman SanjairajDivision of Engineering, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
Rakesh Kumar BeheraDepartment of Mechanical and Aerospace Engineering, NYU Tandon School of Engineering, Brooklyn, New York, USA.
James E SmaySchool of Materials Science and Engineering, Oklahoma State University, Tulsa, Oklahoma, USA.
Nikhil GuptaDepartment of Mechanical and Aerospace Engineering, NYU Tandon School of Engineering, Brooklyn, New York, USA.
Paulo G CoelhoDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Lukasz WitekBiomaterials Division, NYU Dentistry, New York, New York, USA.ORCID 0000-0003-1458-6527

Funding

Field Emission Scanning Electron MicroscopeS10OD026989 · OD · NEW YORK UNIVERSITY · PI BROMAGE, TIMOTHY G. · 2019 to 2019
$581k
NIH HHS S10 OD026989
6 · The paper itself

Abstract

There is an ever-evolving need of customized, anatomic-specific grafting materials for bone regeneration. More specifically, biocompatible and osteoconductive materials, that may be configured dynamically to fit and fill defects, through the application of an external stimulus. The objective of this study was to establish a basis for the development of direct inkjet writing (DIW)-based shape memory polymer-ceramic composites for bone tissue regeneration applications and to establish material behavior under thermomechanical loading. Polymer-ceramic (polylactic acid [PLA]/β-tricalcium phosphate [β-TCP]) colloidal gels were prepared of different w/w ratios (90/10, 80/20, 70/30, 60/40, and 50/50) through polymer dissolution in acetone (15% w/v). Cytocompatibility was analyzed through Presto Blue assays. Rheological properties of the colloidal gels were measured to determine shear-thinning capabilities. Gels were then extruded through a custom-built DIW printer. Space filling constructs of the gels were printed and subjected to thermomechanical characterization to measure shape fixity (R

Indexed as

Calcium PhosphatesPolyestersTissue EngineeringBone RegenerationGelsHumansPolymersPrinting, Three-DimensionalTissue Scaffoldsbeta-tricalcium phosphateCalcium PhosphatesGelsPolyesterspoly(lactide)Polymers3D printingbone tissue engineeringcompositesshape memory

Identifiers

PMID38520704
PMCPMC11003728

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.