Evidence map›Paper›PMID 38520636›Full record

ArticleTissue engineering and regenerative medicine2024

Characterization of Gold-Enhanced Titania: Boosting Cell Proliferation and Combating Bacterial Infestation.

Touseef Amna, M Shamshi Hassan, Jari S Algethami, Alya Aljuaid, Anas Alfarsi, Rasha Alnefaie, Faheem A Sheikh, Myung-Seob Khil

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering and regenerative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Touseef AmnaDepartment of Biology, Faculty of Science, Al-Baha University, P.O. Box 1988, 65799, Al-Baha, Saudi Arabia. touseefamna@gmail.com.
M Shamshi HassanDepartment of Chemistry, Faculty of Science, Al-Baha University, P.O. Box 1988, 65799, Al-Baha, Saudi Arabia. hassan4nano@gmail.com.
Jari S AlgethamiDepartment of Chemistry, College of Science and Arts, Najran University, P.O. Box 1988, 11001, Najran, Saudi Arabia.
Alya AljuaidDepartment of Biology, College of Science and Humanities, Shaqra University, Shaqra, Saudi Arabia.
Anas AlfarsiDepartment of Chemistry, Faculty of Science, Al-Baha University, P.O. Box 1988, 65799, Al-Baha, Saudi Arabia.
Rasha AlnefaieDepartment of Biology, Faculty of Science, Al-Baha University, P.O. Box 1988, 65799, Al-Baha, Saudi Arabia.
Faheem A SheikhNanostructured and Biomimetic Lab, Department of Nanotechnology, University of Kashmir, Hazratbal, Srinagar, Jammu and Kashmir, 190006, India.
Myung-Seob KhilDepartment of Organic Materials and Textile Engineering, Jeonbuk National University, Jeonju, 54896, Republic of Korea. mskhil@jbnu.ac.kr.
Al Baha University · SAJeonbuk National University · KRNajran University · SAShaqra University · SAUniversity of Kashmir · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study an approach was made to efficaciously synthesize gold enhanced titania nanorods by electrospinning. This study aims to address effects of gold enhanced titania nanorods on muscle precursor cells. Additionally, implant related microbial infections are prime cause of various disastrous diseases. So, there is predictable demand for synthesis of novel materials with multifunctional adaptability.

methodsHerein, gold nanoparticles were attached on titania nanorods and described using many sophisticated procedures such as XRD, SEM, EDX and TEM. Antimicrobial studies were probed against Gram-negative Escherichia coli. C2C12 cell lines were exposed to various doses of as-prepared gold enhanced titania nanorods in order to test in vitro cytotoxicity and proliferation. Cell sustainability was assessed through Cell Counting Kit-8 assay at regular intervals. A phase-contrast microscope was used to examine morphology of exposed C2C12 cells and confocal laser scanning microscope was used to quantify cell viability.

resultsThe findings indicate that titania nanorods enhanced with gold exhibit superior antimicrobial efficacy compared to pure titania. Furthermore, newly synthesized gold-enhanced titania nanorods illustrate that cell viability follows a time and concentration dependent pattern.

conclusionConsequently, our study provides optimistic findings indicating that titania nanorods adorned with gold hold significant potential as foundational resource for developing forthcoming antimicrobial materials, suitable for applications both in medical and biomedical fields. This work also demonstrates that in addition to being extremely biocompatible, titania nanorods with gold embellishments may be used in a range of tissue engineering applications in very near future.

Indexed as

Cell ProliferationEscherichia coliGoldNanotubesTitaniumAnimalsAnti-Bacterial AgentsCell LineCell SurvivalMetal NanoparticlesMiceAnti-Bacterial AgentsGoldTitaniumtitanium dioxideAntimicrobial activityAu@TiO2NRsElectrospinningMyoblastsTissue engineering

Identifiers

PMID38520636
PMCPMC11187044
OpenAlexW4393113587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.