Evidence map›Paper›PMID 38520186›Full record

ArticleEuropean journal of neurology2024

Compassionate mind training for people with Parkinson's disease: A pilot study and predictors of response.

Silvia Della Morte, Elena Berti, Carolina Lalli, Nicola Modugno, Francesca Morgante, Anette Schrag, Elena Makovac, Lucia Ricciardi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Lifestyle medicine in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Experiences of Living With the Nonmotor Symptoms of Parkinson's Disease: A Photovoice Study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Silvia Della MorteParkinZone Onlus, Rome, Italy.
Elena BertiParkinZone Onlus, Rome, Italy.
Carolina LalliParkinZone Onlus, Rome, Italy.
Nicola ModugnoParkinZone Onlus, Rome, Italy.
Francesca MorganteNeurosciences Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK.ORCID 0000-0002-9834-3639
Anette SchragDepartment of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, UCL, London, UK.ORCID 0000-0002-9872-6680
Elena MakovacNeurosciences Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK.
Lucia RicciardiNeurosciences Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK.ORCID 0000-0001-9401-3301
Associazione Italiana Vulvodinia Onlus · ITSt George's, University of London · GBIstituto Neurologico Mediterraneo · ITQueen Mary University of London · GBWellcome Centre for Human Neuroimaging · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeople with Parkinson's disease (PD) often present with disabling neuropsychiatric symptoms. Compassionate mind training (CMT) is a psychological approach effective in reducing stress and promoting psychological well-being. Heart rate variability (HRV), a measure reflecting sympathovagal balance, has been associated with psychological well-being and a compassionate attitude.

aimTo assess the feasibility and effectiveness of CMT in enhancing the quality of life and psychological well-being in PD patients. Additionally, we evaluated HRV as a physiomarker for assessing the CMT outcomes.

methodsTwenty-four PD patients participated in the study. A 6-week online CMT intervention was delivered on a weekly basis. At baseline and post-intervention patients completed questionnaires assessing depression, anxiety and quality of life. In a subsample of 11 patients, HRV was measured at baseline and post-intervention in three conditions: at rest, during stress and after 3 min of deep breathing.

resultsThe attendance rate was 94.3%. Quality of life and perceived stigma improved post-intervention as compared with baseline (p = 0.02 and p = 0.03 for PD Questionnaire-39 total score and Stigma subscore, respectively). After CMT, patients presented better physiological regulation to stress, as measured by higher HRV as compared with baseline (p = 0.005). Notably, patients who were more resilient to stress at baseline (less decrease in HRV during stress) experienced a more substantial reduction in anxiety and depression following CMT.

conclusionsCMT is feasible and can improve quality of life and stigma in PD patients. HRV emerges as a promising physiomarker for predicting and measuring the outcomes of psychological interventions in PD.

Indexed as

Heart RateParkinson DiseaseQuality of LifeAgedAnxietyDepressionEmpathyFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsStress, PsychologicalTreatment Outcomecompassionheart rate variabilityneuropsychiatric symptomsParkinson's diseasestigma

Identifiers

PMID38520186
PMCPMC11236006
OpenAlexW4393118604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.