Evidence map›Paper›PMID 38520164›Full record

SynthesisCancer medicine2024

Physical function patient-reported outcomes among adolescent and young adult cancer survivors: A systematic review.

Sarah Tanner, Teyl Engstrom, Cheryl Forbes, Dhaval Patel, Wen Ray Lee, Rick Walker, Natalie Bradford, Jason D Pole

Open access · goldAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. "I had no idea what to expect": adolescent and young adults with cancer identify opportunities for patient-centered anticipatory guidance through narrative writing.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sarah TannerCentre for Health Services Research, The University of Queensland, Herston, Queensland, Australia.ORCID 0000-0001-5115-9503
Teyl EngstromCentre for Health Services Research, The University of Queensland, Herston, Queensland, Australia.ORCID 0000-0002-1778-5006
Cheryl ForbesCentre for Health Services Research, The University of Queensland, Herston, Queensland, Australia.ORCID 0000-0003-3934-3310
Dhaval PatelCentre for Health Services Research, The University of Queensland, Herston, Queensland, Australia.ORCID 0000-0001-6632-5383
Wen Ray LeeChild Health Research Centre, The University of Queensland, South Brisbane, Queensland, Australia.ORCID 0000-0002-9386-9412
Rick WalkerSchool of Medicine, The University of Queensland, Herston, Queensland, Australia.ORCID 0000-0002-2118-8386
Natalie BradfordCancer and Palliative Care Outcomes Centre at Centre for Children's Health Research, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0003-1602-4544
Jason D PoleCentre for Health Services Research, The University of Queensland, Herston, Queensland, Australia.ORCID 0000-0002-0413-5434
Queensland Health · AUThe University of Queensland · AUQueensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe physical challenges faced by adolescents and young adults (AYA) after a cancer diagnosis may be different from those experienced by paediatric and older adult cancer patients. Patient-reported outcome measures (PROMs) are valuable tools that can be useful in exploring the experiences of AYAs and identifying important issues, recurrent themes and areas to potentially improve quality of life.

objectiveWe compared patient-reported physical function outcomes between AYAs diagnosed with cancer and non-cancer controls.

methodThis paper builds on a scoping review published in early 2023 and focuses on PROMs related to physical function.

resultsThis systematic review includes 16 studies that measured and reported on physical function PROMs in AYA cancer survivors compared with their cancer-free peers. Of these studies, 14 found that physical function in AYA survivors was significantly worse. This paper also includes a meta-analysis conducted on 5 studies using the EORTC-QLQ-C30 to measure physical function, which found that physical function score was an average of 7.03 (95% CI: -10.21, -3.86) points lower in the AYA cancer group, compared to their cancer free-peers, a difference that is clinically meaningful.

conclusionsThe results overwhelmingly demonstrate that AYAs post a cancer diagnosis have worse health-related quality of life from a physical function perspective than their cancer-free peers, providing a compelling argument for the need to address this issue. All but one of the studies were cross-sectional, which highlights the need for further assessment of this group longitudinally throughout their cancer journey.

Indexed as

Cancer SurvivorsNeoplasmsPatient Reported Outcome MeasuresQuality of LifeAdolescentFemaleHumansMalePhysical Functional PerformanceYoung Adultadolescentcancercancer survivorspatient‐reported outcome measuresphysical functionroutinely collected health datayoung adult

Identifiers

PMID38520164
PMCPMC10960160
OpenAlexW4393115777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.