Evidence map›Paper›PMID 38520018›Full record

ArticleHealth research policy and systems2024

Intriguing insight into unanswered questions about Mpox: exploring health policy implications and considerations.

Emery Manirambona, Sheharyar Hassan Khan, Abdelmonem Siddiq, Khaled Albakri, Hazem Mohamed Salamah, Noheir Ashraf Ibrahem Fathy Hassan, Shuaibu Saidu Musa, Kuldeep Dhama

Abstract readLetter
In one paragraph

Article in Health research policy and systems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emery ManirambonaCollege of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda. manemery1@gmail.com.ORCID http://orcid.org/0000-0002-0579-3607
Sheharyar Hassan KhanKing Edward Medical University, Lahore, Pakistan.ORCID http://orcid.org/0000-0002-1219-6376
Abdelmonem SiddiqFaculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.ORCID http://orcid.org/0000-0003-3826-9702
Khaled AlbakriFaculty of Medicine, The Hashemite University, Zarqa, Jordan.ORCID http://orcid.org/0000-0003-1462-4204
Hazem Mohamed SalamahFaculty of Medicine, Zagazig University, Zagazig, Egypt.ORCID http://orcid.org/0000-0002-2291-8862
Noheir Ashraf Ibrahem Fathy HassanFaculty of Medicine, Aswan University, Aswan, Egypt.ORCID http://orcid.org/0000-0001-7865-4213
Shuaibu Saidu MusaDepartment of Nursing Science, Ahmadu Bello University, Zaria, Nigeria.ORCID http://orcid.org/0000-0003-0138-3261
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute (IVRI), Izatnagar, Bareilly, Uttar Pradesh, 243122, India.ORCID http://orcid.org/0000-0001-7469-4752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2022 multi-country Monkeypox (Mpox) outbreak has added concerns to scientific research. However, unanswered questions about the disease remain. These unanswered questions lie in different aspects, such as transmission, the affected community, clinical presentations, infection and prevention control and treatment and vaccination. It is imperative to address these issues to stop the spread and transmission of disease. We documented unanswered questions with Mpox and offered suggestions that could help put health policy into practice. One of those questions is why gay, bisexual or other men who have sex with men (gbMSM) are the most affected community, underscoring the importance of prioritizing this community regarding treatment, vaccination and post-exposure prophylaxis. In addition, destigmatizing gbMSM and implementing community-based gbMSM consultation and action alongside ethical surveillance can facilitate other preventive measures such as ring vaccination to curb disease transmission and track vaccine efficacy. Relevant to that, vaccine and drug side effects have implied the questionability of their use and stimulated the importance of health policy development regarding expanded access and off-label use, expressing the need for safe drug and vaccine development manufacturing. The possibility of reverse zoonotic has also been raised, thus indicating the requirement to screen not only humans, but also their related animals to understand the real magnitude of reverse zoonosis and its potential risks. Implementing infection prevention and control measures to stop the virus circulation at the human-animal interface that includes One Health approach is essential.

Indexed as

Mpox, MonkeypoxSexual and Gender MinoritiesAnimalsHealth PolicyHomosexuality, MaleHumansMaleZoonosesHealth PolicyMonkeypoxMpoxMysteriesPrevention controlsTreatmentUnanswered questionsVaccines

Identifiers

PMID38520018
PMCPMC10960492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.