Evidence map›Paper›PMID 38520005›Full record

ArticleJournal of medical case reports2024

Primary alveolar rhabdomyosarcoma of the brain: a case report.

Layal Al Mahmasani, Marwan Najjar, Roula Hourany, Abeer Tabbarah, Sara Sinno, Nathalie Chamseddine, Reine Abou Zeidane, Ghid Amhaz, Bassem Youssef, Hazem I Assi

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Layal Al MahmasaniDivision of Haematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, P.O. Box: 11-0236, Beirut, 1107 2020, Lebanon.
Marwan NajjarDivision of Neurosurgery, Department of Surgery, American University of Beirut Medical Centre, Beirut, Lebanon.
Roula HouranyDepartment of Diagnostic Radiology, American University of Beirut Medical Centre, Beirut, Lebanon.
Abeer TabbarahDepartment of Pathology, American University of Beirut Medical Centre, Beirut, Lebanon.
Sara SinnoDepartment of Pathology, American University of Beirut Medical Centre, Beirut, Lebanon.
Nathalie ChamseddineDivision of Haematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, P.O. Box: 11-0236, Beirut, 1107 2020, Lebanon.
Reine Abou ZeidaneDivision of Haematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, P.O. Box: 11-0236, Beirut, 1107 2020, Lebanon.
Ghid AmhazDivision of Haematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, P.O. Box: 11-0236, Beirut, 1107 2020, Lebanon.
Bassem YoussefDepartment of Radiation Oncology, American University of Beirut Medical Centre, Beirut, Lebanon.
Hazem I AssiDivision of Haematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, P.O. Box: 11-0236, Beirut, 1107 2020, Lebanon. ha157@aub.edu.lb.
American University of Beirut · LBAmerican University of Beirut Medical Center · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary brain rhabdomyosarcoma is a rare primary brain malignancy with few case reports. The vast majority of cases of primary brain rhabdomyosarcoma occur in pediatric patients, and immunohistochemistry can distinguish it from embryonal subtypes; however, few cases of primary brain rhabdomyosarcoma in adults have been reported in the literature. CASE PRESENTATION: We report the case of a 26-year-old White male patient who was found to have primary brain alveolar rhabdomyosarcoma after developing headaches for several months. A brain MRI revealed a mixed cystic and solid tumor along the vermis of the cerebellum. The patient underwent a gross total surgical resection, which confirmed the diagnosis of alveolar rhabdomyosarcoma. Further staging workup for another primary focus or disseminated disease yielded negative results, confirming the diagnosis of primary alveolar rhabdomyosarcoma of the brain.

conclusionThe standard of care for managing this rare type of brain tumor involves surgery with adjuvant chemoradiotherapy. Further studies should be conducted for a better diagnostic and therapeutic understanding.

Indexed as

Brain NeoplasmsRhabdomyosarcomaRhabdomyosarcoma, AlveolarRhabdomyosarcoma, EmbryonalAdultBrainHumansMagnetic Resonance ImagingMaleIntracranialMultidisciplinary approachPrimary alveolar rhabdomyosarcoma

Identifiers

PMID38520005
PMCPMC10960377
OpenAlexW4394757868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.