Evidence map›Paper›PMID 38519839›Full record

ReviewMolecular oncology2024

Minimally invasive biopsy-based diagnostics in support of precision cancer medicine.

Bo Franzén, Gert Auer, Rolf Lewensohn

Open access · goldAbstract readReview
In one paragraph

Review in Molecular oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bo FranzénDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-1234-4981
Gert AuerDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Rolf LewensohnDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Karolinska University Hospital · SEKarolinska Institutet · SE

Funding

Cancer Centrum Karolinska (CCK) Research FoundationCancerfonden CAN 2018/597Cancerfonden CAN 2021/1469Stockholm County Council 750032Stockholm County Council 909121The Cancer Society in Stockholm 221212The Hans Wigzell Research Foundation
6 · The paper itself

Abstract

Precision cancer medicine (PCM) to support the treatment of solid tumors requires minimally invasive diagnostics. Here, we describe the development of fine-needle aspiration biopsy-based (FNA) molecular cytology which will be increasingly important in diagnostics and adaptive treatment. We provide support for FNA-based molecular cytology having a significant potential to replace core needle biopsy (CNB) as a patient-friendly potent technique for tumor sampling for various tumor types. This is not only because CNB is a more traumatic procedure and may be associated with more complications compared to FNA-based sampling, but also due to the recently developed molecular methods used with FNA. Recent studies show that image-guided FNA in combination with ultrasensitive molecular methods also offers opportunities for characterization of the tumor microenvironment which can aid therapeutic decisions. Here we provide arguments for an increased implementation of molecular FNA-based sampling as a patient-friendly diagnostic method, which may, due to its repeatability, facilitate regular sampling that is needed during different treatment lines, to provide tumor information, supporting treatment decisions, shortening lead times in healthcare, and benefit healthcare economics.

Indexed as

NeoplasmsPrecision MedicineBiopsy, Fine-NeedleHumansMinimally Invasive Surgical Proceduresbiomarkersfine‐needle aspiratesimmune signalingminimally invasive diagnosticssolid tumorstumor microenvironment

Identifiers

PMID38519839
PMCPMC11547246
OpenAlexW4393116920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.