Evidence map›Paper›PMID 38519750›Full record

ArticleApplied biochemistry and biotechnology2024

Exploring the Phytochemical Diversity and Antioxidant Potential of the Vietnamese Smilax glabra Roxb: Insights from UPLC-QTOF-MS/MS and Zebrafish Model Studies.

Vu Thanh Nguyen, Vo Thi Minh Thao, Le Luu Phuong Hanh, Thi Hoa Rol, Ngo Huynh Phuong Thao, Tong Xuan Nguyen, Pham Thanh Luu, Dinh Thi Thuy

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Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Vu Thanh NguyenBiotechnology Center of Ho Chi Minh City, Ho Chi Minh City, Vietnam. nt.vu@hutech.edu.vn.ORCID http://orcid.org/0000-0002-3458-8813
Vo Thi Minh ThaoBiotechnology Center of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Le Luu Phuong HanhBiotechnology Center of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Thi Hoa RolBiotechnology Center of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Ngo Huynh Phuong ThaoBiotechnology Center of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Tong Xuan NguyenInstitute of Environmental Science, Industrial University of Ho Chi Minh City, Engineering, and Management, Ho Chi Minh City, Vietnam.
Pham Thanh LuuInstitute of Tropical Biology, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam.
Dinh Thi ThuyDepartment of Engineering and Technology, Van Hien University, 665-667-669 Dien Bien Phu Street, Ho Chi Minh City, Vietnam.
Ho Chi Minh City University of Technology · VNIndustrial University of Ho Chi Minh City · VNVăn Hiến University · VNVietnam Academy of Science and Technology · VN

Funding

National Foundation for Science and Technology Development 108.06-2020.19
6 · The paper itself

Abstract

Research on natural products is growing due to their potential health benefits and medicinal properties. Despite regional variations in phytochemical composition and bioactivity, Smilax glabra Roxb (SGB) has attracted the interest of researchers. Scientists are particularly interested in the Vietnamese SGB variant, which is influenced by biological and environmental factors. Despite geographical differences in phytochemical makeup and bioactivities, SGB remains a fascinating subject in traditional herbal medicine. Using ultra-performance liquid chromatography and quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS), the phytochemicals in Vietnamese SGB extracts were investigated. This study revealed a wide range of phytochemical compounds, including flavonoids, terpenoids, glycosides, alkaloids, organic acids, phenolics, and steroids. Furthermore, utilizing zebrafish as a model organism, we discovered that these extracts have the surprising ability to greatly improve the survival rate of zebrafish larvae exposed to oxidative stress caused by arsenite (NaAsO

Indexed as

AntioxidantsPhytochemicalsPlant ExtractsSmilaxAnimalsChromatography, High Pressure LiquidOxidative StressTandem Mass SpectrometryVietnamZebrafishAntioxidantsPhytochemicalsPlant ExtractsKeap1/Nrf2-independent pathwaysNatural antioxidantsPhytochemical analysisSmilax glabra RoxbUPLC-QTOF-MS/MSZebrafish

Identifiers

PMID38519750
OpenAlexW4394764034

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.