Evidence map›Paper›PMID 38519111›Full record

ArticleRMD open2024

Sex differences in cytokines and adipokines in obese patients with PsA and controls undergoing a weight loss intervention.

Anton Jonatan Landgren, Charlotte A Jonsson, Annelie Bilberg, Björn Eliasson, Linda Torres, Mats Dehlin, Lennart Jacobsson, Inger Gjertsson, Ingrid Larsson, Eva Klingberg

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Anton Jonatan LandgrenDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden anton.landgren@rheuma.gu.se.ORCID 0000-0001-7922-3335
Charlotte A JonssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Annelie BilbergInstitute of Neuroscience and Physiology, Section of Health and Rehabilitation, Physiotherapy, Sahlgrenska Academy, Gothenburg, Sweden.
Björn EliassonDepartment of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Linda TorresDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Mats DehlinDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lennart JacobssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Inger GjertssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ingrid LarssonDepartment of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Eva KlingbergDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-6858-6413
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SENational Academy of Medicine · USRegion Västra Götaland · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this post hoc analysis of a previously published study, we compared cytokines and adipokine levels in women and men with psoriatic arthritis (PsA) at baseline (BL) and 6 months (M6) following a weight loss intervention.

methodsPatients with PsA (n=41) between 25 and 75 years of age, with body mass index (BMI)≥33 kg/m

resultsAt BL, serum levels of interleukin (IL)-23, leptin and high molecular weight-adiponectin were higher in women with PsA compared with men, whereas serum levels of interferon (IFN)-γ, IL-12/IL-23 p40 and IL-13 were significantly lower in women. Serum IL-23 was significantly reduced at M6 compared with BL in women but not in men with PsA. In women with PsA, the reduction in IL-23 at M6, ∆IL-23, were positively correlated with ∆Disease Activity Score 28 C reactive protein (CRP) (Spearman's correlation (r

conclusionsWomen and men with PsA differed with regard to serum levels of cytokines and adipokines before and after weight loss.

Indexed as

AdipokinesArthritis, PsoriaticAdiponectinC-Reactive ProteinCytokinesFemaleHumansInterleukin-23MaleObesitySex CharacteristicsWeight LossAdipokinesAdiponectinC-Reactive ProteinCytokinesInterleukin-23Arthritis, PsoriaticCytokinesInflammation

Identifiers

PMID38519111
PMCPMC10961525
OpenAlexW4393098865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.