Evidence map›Paper›PMID 38518792›Full record

ReviewThe Lancet. Microbe2024

Staphylococcus aureus colonisation and strategies for decolonisation.

Pipat Piewngam, Michael Otto

Open access · goldAbstract readReview
In one paragraph

Review in The Lancet. Microbe, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
49.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 126 citations in OpenAlex.

  1. Trial
  2. Antibacterial and Antibiofilm Activity ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026
    Review
  7. Review
  8. Genomic diversity and topical antimicrobial resistance inAntimicrobial agents and chemotherapy · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Characterization of beddomeilactone amide as bacterial DNA gyrase inhibitor: in vitro evaluation and computational insights.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  13. Biofilm sensitization to breakJournal of medical microbiology · 2026
    Article
  14. iScience · 2026
    Article
  15. Article
  16. Article
  17. ThebioRxiv : the preprint server for biology · 2026
    Article
  18. Article
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pipat PiewngamPathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD, USA.
Michael OttoPathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD, USA. Electronic address: motto@niaid.nih.gov.
National Institutes of Health · US

Funding

Staphylococcal pathogenesisZIAAI000904 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI OTTO, MICHAEL · 2009 to 2025
$22.6M
Role of the human microbiota and probioticsZIAAI001080 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI OTTO, MICHAEL · 2009 to 2025
$9.7M
Pathogenesis of staphylococcal biofilm-related infectionZ01AI001080 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI OTTO, MICHAEL · 2008 to 2008
$329k
Intramural NIH HHS Z01 AI001080Intramural NIH HHS ZIA AI000904Intramural NIH HHS ZIA AI001080
6 · The paper itself

Abstract

Staphylococcus aureus is a leading cause of death by infectious diseases worldwide. Treatment of S aureus infections is difficult due to widespread antibiotic resistance, necessitating alternative approaches and measures for prevention of infection. Because S aureus infections commonly arise from asymptomatic colonisation, decolonisation is considered a key approach for their prevention. Current decolonisation procedures include antibiotic-based and antiseptic-based eradication of S aureus from the nose and skin. However, despite the widespread implementation and partial success of such measures, S aureus infection rates remain worrisome, and resistance to decolonisation agents is on the rise. In this Review we outline the epidemiology and mechanisms of S aureus colonisation, describe how colonisation underlies infection, and discuss current and novel approaches for S aureus decolonisation, with a focus on the latest findings on probiotic strategies and the intestinal S aureus colonisation site.

Indexed as

Anti-Bacterial AgentsCarrier StateStaphylococcal InfectionsStaphylococcus aureusHumansProbioticsAnti-Bacterial Agents

Identifiers

PMID38518792
PMCPMC11162333
OpenAlexW4392935370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.