Evidence map›Paper›PMID 38517971›Full record

ArticleScience advances2024

Chemosensory detection of polyamine metabolites guides

Benjamin Brissette, Lia Ficaro, Chenguang Li, Drew R Jones, Sharad Ramanathan, Niels Ringstad

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Nematicidal indole oxazoles and chemoattractants from soil bacteria.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. The anticonvulsant and mood-stabilizing drug valproic acid attractsbioRxiv : the preprint server for biology · 2025
    Article
  6. Review
  7. Food sensing controlsScience advances · 2025
    Article
  8. Valeric acid attractsmicroPublication biology · 2025
    Article
  9. Metabolites limiting predator growth wane with prey biodiversity.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benjamin BrissetteDepartment of Cell Biology, Neuroscience and Physiology, Neuroscience Institute, NYU School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-8652-5208
Lia FicaroDepartment of Biochemistry and Pharmacology, NYU School of Medicine, New York, NY 10016, USA.
Chenguang LiBiophysics Program, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-2884-6414
Drew R JonesDepartment of Biochemistry and Pharmacology, NYU School of Medicine, New York, NY 10016, USA.ORCID 0000-0001-8732-9818
Sharad RamanathanDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-9445-1248
Niels RingstadDepartment of Cell Biology, Neuroscience and Physiology, Neuroscience Institute, NYU School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-8679-2269
Harvard University · USNeurosciences Institute · USNew York University · US

Funding

MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008313 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MURTHY, VENKATESH N · 1989 to 2023
$14.6M
Molecular genetics of sensory modulation of motor programsR35GM122573 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Niels Ringstad · 2017 to 2026
$5.7M
Mechanisms of Synaptic Dopamine Signaling in the Control of BehaviorR01NS117908 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RAMANATHAN, SHARAD, RINGSTAD, NIELS · 2020 to 2024
$2.6M
Training Program in Molecular, Cellular, and Translational NeuroscienceT32NS086750 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JEREMY S DASEN, Katherine Nagel · 2014 to 2026
$2.4M
Neural and molecular mechanisms of microbe-sensing in the control of animal behavior - Resubmission - 1F31DC019045 · NIDCD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BRISSETTE, BENJAMIN · 2021 to 2022
$76k
NIDCD NIH HHS F31 DC019045NIGMS NIH HHS R35 GM122573NIGMS NIH HHS T32 GM008313NINDS NIH HHS R01 NS117908NINDS NIH HHS T32 NS086750
6 · The paper itself

Abstract

Much is known about molecular mechanisms by which animals detect pathogenic microbes, but how animals sense beneficial microbes remains poorly understood. The roundworm

Indexed as

Caenorhabditis elegansPolyaminesAnimalsEscherichia coliPutrescineSpermidinePolyaminesPutrescineSpermidine

Identifiers

PMID38517971
PMCPMC10959419
OpenAlexW4393079281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.