Evidence map›Paper›PMID 38517577›Full record

ArticleInsights into imaging2024

Evaluation of endometrial receptivity in women with unexplained infertility by shear wave elastography.

Zheng-Ying Li, Lu Cai, Zhi-Jun Zhang, Hai-Rong Zou, Mei He, Mei-Lin Qin, Hui Wang

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Application of artificial intelligence to ultrasound imaging for benign gynecological disorders: systematic review.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Pooled it
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zheng-Ying LiDepartment of Ultrasound, University-Town Hospital of Chongqing Medical University, No. 55 University Middle Road, Shapingba District, Chongqing, 401331, China.
Lu CaiDepartment of Ultrasound, University-Town Hospital of Chongqing Medical University, No. 55 University Middle Road, Shapingba District, Chongqing, 401331, China.
Zhi-Jun ZhangDepartment of Ultrasound, University-Town Hospital of Chongqing Medical University, No. 55 University Middle Road, Shapingba District, Chongqing, 401331, China.
Hai-Rong ZouDepartment of Ultrasound, University-Town Hospital of Chongqing Medical University, No. 55 University Middle Road, Shapingba District, Chongqing, 401331, China.
Mei HeDepartment of Ultrasound, University-Town Hospital of Chongqing Medical University, No. 55 University Middle Road, Shapingba District, Chongqing, 401331, China.
Mei-Lin QinDepartment of Ultrasound, University-Town Hospital of Chongqing Medical University, No. 55 University Middle Road, Shapingba District, Chongqing, 401331, China.
Hui WangDepartment of Ultrasound, University-Town Hospital of Chongqing Medical University, No. 55 University Middle Road, Shapingba District, Chongqing, 401331, China. 792591079@qq.com.
Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe endometrium of most unexplained infertility (UI) patients has been altered histologically. Shear wave elastography (SWE) is utilized to assess the signature of living tissue. This study aimed to explore the value of SWE in evaluating endometrial receptivity (ER) in UI patients.

methodsIn total, 59 UI patients (UI group) and 52 normal control women (NC group) who received fertility consultation in our hospital were included between January 2022 and June 2023. We divided them into the late-proliferative phase of UI group (LPUI; n = 59), mid-secretory phase of UI group (MPUI; n = 41), late-proliferative phase of NC group (LPNC; n = 52), and mid-secretory phase of NC group (MPNC; n = 45). Transvaginal ultrasonography and SWE were performed during the LP and MP. Endometrial thickness (EMT), uterine artery pulsatility index (UA-PI), endometrial mean elasticity (E-mean), and mean shear wave velocities (SWV-mean) were measured.

resultsThere were significant differences in E-mean, SWV-mean, EMT, and UA-PI between the UI group and the NC group during both the LP and MP (p

conclusionsUI patients exhibited thinner endometrium, increased endometrial stiffness, and poor endometrial blood perfusion. E-mean was the most effective parameter to evaluate ER in UI patients. The study preliminarily proved that SWE is a promising non-invasive tool for evaluating the condition of endometrium. CRITICAL RELEVANCE STATEMENT: This study aimed to explore the significance of endometrial elasticity measured by SWE in evaluating patients with UI. The findings revealed a correlation between EMT, UA-PI, and E-mean. Endometrial elasticity can serve as an effective indicator for predicting ER. KEY POINTS: 1. To explore the significance of endometrial elasticity in assessing patients with UI. 2. The endometrium of UI patient exhibited thinness, stiffness, and poor blood perfusion. 3. Endometrial elasticity serves as a valuable indicator for evaluating endometrial receptivity.

Indexed as

ElasticityEndometrial receptivityEndometriumShear wave elastographyUnexplained infertility

Identifiers

PMID38517577
PMCPMC10959862
OpenAlexW4393067805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.