Evidence map›Paper›PMID 38517457›Full record

ArticleJMIR formative research2024

Automated Category and Trend Analysis of Scientific Articles on Ophthalmology Using Large Language Models: Development and Usability Study.

Hina Raja, Asim Munawar, Nikolaos Mylonas, Mohammad Delsoz, Yeganeh Madadi, Muhammad Elahi, Amr Hassan, Hashem Abu Serhan, Onur Inam, Luis Hernandez and 5 more

Abstract read
In one paragraph

Article in JMIR formative research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hina RajaDepartment of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, United States.ORCID https://orcid.org/0000-0002-5268-047X
Asim MunawarWatson Research Center, IBM Research, New York, NY, United States.ORCID https://orcid.org/0009-0002-6504-6096
Nikolaos MylonasSchool of Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0002-5733-543X
Mohammad DelsozDepartment of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, United States.ORCID https://orcid.org/0000-0001-5638-2034
Yeganeh MadadiDepartment of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, United States.ORCID https://orcid.org/0000-0003-4292-3404
Muhammad ElahiQuillen College of Medicine, East Tennessee State University, Johnson, TN, United States.ORCID https://orcid.org/0009-0005-0451-4206
Amr HassanGavin Herbert Eye Institute, School of Medicine, University of California, Irvine, CA, United States.ORCID https://orcid.org/0000-0002-8281-9268
Hashem Abu SerhanDepartment of Ophthalmology, Hamad Medical Corporation, Doha, Qatar.ORCID https://orcid.org/0000-0002-2953-2188
Onur InamEdward S. Harkness Eye Institute, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.ORCID https://orcid.org/0000-0002-4726-1190
Luis HernandezAssociation to Prevent Blindness in Mexico, Ciudad, Mexico.ORCID https://orcid.org/0009-0008-7233-5498
Hao ChenDepartment of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, United States.ORCID https://orcid.org/0000-0002-2680-6921
Sang TranDepartment of Ophthalmology and Visual Sciences, School of Medicine, University of Maryland, Baltimore, MD, United States.ORCID https://orcid.org/0000-0001-7287-6122
Wuqaas MunirDepartment of Ophthalmology and Visual Sciences, School of Medicine, University of Maryland, Baltimore, MD, United States.ORCID https://orcid.org/0000-0001-8070-6668
Alaa Abd-AlrazaqAI Center for Precision Health, Weill Cornell Medicine-Qatar, Doha, Qatar.ORCID https://orcid.org/0000-0001-7695-4626
Siamak YousefiDepartment of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, United States.ORCID https://orcid.org/0000-0002-2855-430X

Funding

Predicting the risk of glaucoma from structural, functional, and genetic factors using artificial intelligenceR01EY033005 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI YOUSEFI, SIAMAK · 2022 to 2025
$2.4M
Improved Glaucoma Monitoring Using Artificial-Intelligence Enabled DashboardR21EY031725 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI YOUSEFI, SIAMAK · 2020 to 2022
$545k
NEI NIH HHS R01 EY033005NEI NIH HHS R21 EY031725
6 · The paper itself

Abstract

backgroundIn this paper, we present an automated method for article classification, leveraging the power of large language models (LLMs).

objectiveThe aim of this study is to evaluate the applicability of various LLMs based on textual content of scientific ophthalmology papers.

methodsWe developed a model based on natural language processing techniques, including advanced LLMs, to process and analyze the textual content of scientific papers. Specifically, we used zero-shot learning LLMs and compared Bidirectional and Auto-Regressive Transformers (BART) and its variants with Bidirectional Encoder Representations from Transformers (BERT) and its variants, such as distilBERT, SciBERT, PubmedBERT, and BioBERT. To evaluate the LLMs, we compiled a data set (retinal diseases [RenD] ) of 1000 ocular disease-related articles, which were expertly annotated by a panel of 6 specialists into 19 distinct categories. In addition to the classification of articles, we also performed analysis on different classified groups to find the patterns and trends in the field.

resultsThe classification results demonstrate the effectiveness of LLMs in categorizing a large number of ophthalmology papers without human intervention. The model achieved a mean accuracy of 0.86 and a mean F

conclusionsThe proposed framework achieves notable improvements in both accuracy and efficiency. Its application in the domain of ophthalmology showcases its potential for knowledge organization and retrieval. We performed a trend analysis that enables researchers and clinicians to easily categorize and retrieve relevant papers, saving time and effort in literature review and information gathering as well as identification of emerging scientific trends within different disciplines. Moreover, the extendibility of the model to other scientific fields broadens its impact in facilitating research and trend analysis across diverse disciplines.

Indexed as

BARTBERTBidirectional and Auto-Regressive Transformersbidirectional encoder representations from transformerslarge language modelLLMophthalmologytext classificationtrend analysis

Identifiers

PMID38517457
PMCPMC10998173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.