Evidence map›Paper›PMID 38517219›Full record

ArticleThe Indian journal of medical research2024

Does Lake Louise questionnaire interpret high-altitude headache as acute mountain sickness? Experience in the western Himalayas.

Abhilash Unnikrishnan, Atul Shekhar, Dharmendra Kumar, Raksha Jaipurkar, Gaurav Sikri, Krishan Singh, Rahul Manral

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Article in The Indian journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Abhilash UnnikrishnanDepartment of Physiology, Armed Forces Medical College, Pune, Maharashtra, India.
Atul ShekharDepartment of Physiology, Armed Forces Medical College, Pune, Maharashtra, India.
Dharmendra KumarDepartment of Physiology, Armed Forces Medical College, Pune, Maharashtra, India.
Raksha JaipurkarDepartment of Physiology, Armed Forces Medical College, Pune, Maharashtra, India.
Gaurav SikriDepartment of Physiology, Armed Forces Medical College, Pune, Maharashtra, India.
Krishan SinghDepartment of Physiology, Armed Forces Medical College, Pune, Maharashtra, India.
Rahul ManralDepartment of Physiology, Armed Forces Medical College, Pune, Maharashtra, India.
Armed Forces Medical College · INDefence Institute of High Altitude Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND

objectivesHigh-altitude headache (HAH) and headache in acute mountain sickness (AMS) are common among lowlanders ascending to the high altitude and are often confused with one another. A pilot study was undertaken to analyze HAH and AMS cases in Indian lowlanders ascending to Leh city (3500 m) in western Himalayas.

methodsA total number of 1228 Indian lowlanders, who ascended (fresh and re-inductees) by air and acclimatized, participated in this pilot study. The intensity of headache was assessed by the Visual Analogue Score. The parameters of HAH as per the International Classification of Headache Disorders-3 and 2018 Revised Lake Louise Questionnaire (LLQ) were used to differentiate HAH and AMS.

resultsOut of 1228 cases, 78 (6.4%) cases had headache, of which 24 (1.95%) cases were HAH only, 40 (3.25%) cases AMS only and 14 (1.14%) cases were defined as both HAH and AMS. There was a significant difference in heart rate [F (2,51) = (4.756), P =0.01] between these groups. It also showed a difference in the correlation between the parameters within the groups. The Odd's Ratio of AMS in fresh and re-inductees was found to be 4.5 and for HAH it was 4.33. INTERPRETATION

conclusionsThe findings of this study suggest that LLQ has a tendency of overestimating AMS by including HAH cases. Furthermore differential parameters exhibit differences when AMS and HAH are considered separately. Re-inductees showed a lower incidence of HAH and AMS.

Indexed as

Altitude SicknessAcute DiseaseAltitudeHeadacheHimalayasHumansPilot ProjectsSurveys and Questionnaires

Identifiers

PMID38517219
PMCPMC11050752
OpenAlexW4394608143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.