Evidence map›Paper›PMID 38517194›Full record

ArticleMicrobiology spectrum2024

Determination of minimum inhibitory concentrations using machine-learning-assisted agar dilution.

Alessandro Gerada, Nicholas Harper, Alex Howard, Nada Reza, William Hope

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Advancements in AI-driven drug sensitivity testing research.Frontiers in cellular and infection microbiology · 2025
    Review
  7. Article
  8. Bayesian Calibration to Address the Challenge of Antimicrobial Resistance: A Review.IEEE access : practical innovations, open solutions · 2024
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alessandro GeradaAntimicrobial Pharmacodynamics and Therapeutics Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-6743-4271
Nicholas HarperAntimicrobial Pharmacodynamics and Therapeutics Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Alex HowardAntimicrobial Pharmacodynamics and Therapeutics Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Nada RezaAntimicrobial Pharmacodynamics and Therapeutics Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0003-1183-3262
William HopeAntimicrobial Pharmacodynamics and Therapeutics Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0001-6187-878X
University of Liverpool · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Effective policy to address the global threat of antimicrobial resistance requires robust antimicrobial susceptibility data. Traditional methods for measuring minimum inhibitory concentration (MIC) are resource intensive, subject to human error, and require considerable infrastructure. AIgarMIC streamlines and standardizes MIC measurement and is especially valuable for large-scale surveillance activities. MICs were measured using agar dilution for IMPORTANCE: This research uses modern artificial intelligence and machine-learning approaches to standardize and automate the interpretation of agar dilution minimum inhibitory concentration testing. Artificial intelligence is currently of significant topical interest to researchers and clinicians. In our manuscript, we demonstrate a use-case in the microbiology laboratory and present validation data for the model's performance against manual interpretation.

Indexed as

AgarAnti-Bacterial AgentsMachine LearningMicrobial Sensitivity TestsEnterobacteriaceaeEscherichia coliHumansNeural Networks, ComputerAgarAnti-Bacterial Agentsantimicrobial resistanceartificial intelligenceassay validationdigital healthimage recognitionlaboratory softwaremachine learningminimum inhibitory concentration

Identifiers

PMID38517194
PMCPMC11064640
OpenAlexW4393096990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.