ArticleHuman vaccines & immunotherapeutics2024
Expanded spectrum of varicella disease and the need for vaccination in India.
Article in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Varicella zoster virus infection.Nature reviews. Disease primers · 2026Review
- Seroprevalence of varicella antibodies in unvaccinated children with nephrotic syndrome in disease remission.The Indian journal of medical research · 2026Article
- Varicella vaccination in children with nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2026Article
- Attitudes of healthcare workers toward recommending vaccination against herpes zoster: a study based on the health belief model and theory of planned behavior.Frontiers in public health · 2026Article
- Global burden of varicella and herpes zoster across 204 countries, 1990-2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.Frontiers in public health · 2025Article
- Diagnostic value of anti-VZV IgG in neurological diseases among varicella unvaccinated individuals.Journal of neurovirology · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Varicella vaccine was first licensed in Japan and South Korea in 1989 for use in healthy children and was introduced in US in 1995. So far, 29 countries have adopted varicella vaccine in their universal immunization program (UIP). No Asian country, India included, has adopted the varicella vaccine as part of their UIP. The extra-cutaneous sites for VZV diseases are central nervous system and gastrointestinal tract, the expanded disease spectrum includes vasculopathy, myelitis, inflammatory bowel disease, perforated ulcers, and gastritis. The actual disease burden of varicella is not known as most of the infected individuals may not visit the physician. The amplifiable VZV DNA will not always be detectable in cerebrospinal fluid (CSF) samples in protracted illnesses such as vasculopathies, but demonstrable anti-VZV IgG in CSF has diagnostic value. The World Health Organization (WHO) position paper 2014 recommends two doses of varicella and zoster vaccines in targeted population. In India, varicella vaccine is not included in the UIP due to the cost and the belief that lifelong immunity occurs following primary infection. The expanded spectrum of VZV disease and the mounting body of evidence, however, suggest the need for both varicella and zoster vaccines in routine immunization schedule.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.