Evidence map›Paper›PMID 38516882›Full record

ArticleSubstance use & addiction journal2025

Connecting Chronic Pain and Opioid Use Disorder Clinical Trials Through Data Harmonization: Wake Forest IMPOWR Dissemination, Education, and Coordination Center (IDEA-CC).

Meredith C B Adams, Robert W Hurley, Umit Topaloglu

Abstract read
In one paragraph

Article in Substance use & addiction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meredith C B AdamsDepartment of Anesthesiology, Biomedical Informatics, Translational Neuroscience, and Public Health Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-3969-4279
Robert W HurleyDepartment of Anesthesiology, Translational Neuroscience and Public Health Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Umit TopalogluDepartment of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Funding

MIRHIQL Resource Center for Improving Quality of Life with Chronic Pain (MRC)R24DA058606 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ADAMS, MEREDITH C. B., HURLEY, ROBERT WILLSON · 2023 to 2023
$6.0M
WF DISC: Navigating Data Solutions for Chronic Pain and Opioid Use DisorderU24DA057612 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MEREDITH C. B. ADAMS · 2022 to 2026
$5.6M
Wake Forest IMPOWR Dissemination Education and Coordination Center (IDEA-CC)R24DA055306 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ADAMS, MEREDITH C. B. · 2021 to 2023
$3.3M
Identifying opioid response phenotypes in low back pain electronic health dataK08EB022631 · NIBIB · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ADAMS, MEREDITH C. B. · 2017 to 2020
$737k
NIAMS NIH HHS L30 AR074165NIBIB NIH HHS K08 EB022631NIDA NIH HHS R24 DA055306NIDA NIH HHS R24 DA058606NIDA NIH HHS U24 DA057612
6 · The paper itself

Abstract

The National Institutes of Health (NIH) has developed the NIH HEAL Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) network to address the interconnected nature of chronic pain (CP) and opioid use disorder (OUD), which are influenced by mental health. The network aims to develop integrated treatment pathways across multiple sites in the United States. The IMPOWR Dissemination, Education, and Coordination Center (IDEA-CC) is proposed to support the NIH HEAL IMPOWR network by developing a CP- and OUD-focused infrastructure that includes measures of stigma, trauma, and quality of life. This includes deploying a data framework to link clinical sites, developing an educational infrastructure to address stigma and health disparities, and disseminating research findings. The IDEA-CC will standardize data collection processes, develop web-based data commons, and facilitate data sharing opportunities. The IDEA-CC will support the development and validation of composite CP and OUD measures and will develop educational materials to address stigma and health disparities. Overall, the IDEA-CC will create a research community and data commons that connect NIH HEAL IMPOWR centers to translate findings and develop a key CP-OUD research data, and education infrastructure.

Indexed as

Chronic PainNational Institutes of Health (U.S.)Opioid-Related DisordersClinical Trials as TopicHumansInformation DisseminationQuality of LifeSocial StigmaUnited Stateschronic paincommon data elementshealthcare disparitiesopioid-related disorderssocial stigma

Identifiers

PMID38516882
PMCPMC11884317

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.