Evidence map›Paper›PMID 38516651›Full record

ArticleWomen's health reports (New Rochelle, N.Y.)2024

Exploratory Analysis of Concordance Between Clinician-Collected and Self-Sampled Human Papillomavirus Tests in a Small Cohort of Average- and High-Risk Patients.

Ashley Wong, Rebecca Morgis, Juliette Entenman, Sarah I Ramirez, Amy L Hays, Tonya S Wright, Christina M Scartozzi, Mack T Ruffin, Jennifer L Moss

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Women's health reports (New Rochelle, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04585243 naterminatednot on this map

HPV Self-sampling Among Women at the Penn State Hershey Colposcopy Clinics

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2020 to 2022Enrolled22ConditionsHPVArmsEvalyn Brush
NCT04591977 naterminatednot on this map

HPV Self-sampling Among Women at Penn State Hershey Well Women Appointments

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2021 to 2022Enrolled46ConditionsHPVArmsHPV Self-Sampling Kit (Evalyn Brush)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ashley WongPenn State College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Rebecca MorgisPenn State College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Juliette EntenmanDepartment of Family and Community Medicine, Penn State College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Sarah I RamirezDepartment of Family and Community Medicine, Penn State College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Amy L HaysDepartment of Family and Community Medicine, Penn State College of Medicine, The Pennsylvania State University, State College, Pennsylvania, USA.
Tonya S WrightDepartment of Obstetrics and Gynecology, Penn State College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Christina M ScartozziDepartment of Family and Community Medicine, Penn State College of Medicine, The Pennsylvania State University, Reading, Pennsylvania, USA.
Mack T RuffinDepartment of Family and Community Medicine, Penn State College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Jennifer L MossDepartment of Family and Community Medicine, Penn State College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Cervical cancer screening rates have stagnated, but self-sampling modalities have the potential to increase uptake. This study compares the test characteristics of self-sampled high-risk human papillomavirus (hrHPV) tests with clinician-collected hrHPV tests in average-risk ( Methods: In this cross-sectional study, a relatively small cohort of average-risk ( Results: Among average-risk participants, hrHPV positivity was 6% for both test methods ( Conclusions: Self-sampled hrHPV testing demonstrated high accuracy for average-risk patients in this exploratory study. However, its performance was less consistent in high-risk patients who had already received an abnormal screening result, which could be attributed to spontaneous viral clearance over time. The limited number of participants, particularly HPV-positive cases, suggests caution in interpreting these results. Further research with larger cohorts is necessary to validate these findings and to explore the integration of self-sampled hrHPV testing into routine clinical care, particularly for patients with a history of cervical abnormalities. Clinical Trial Registration: NCT04591977, NCT04585243.

Indexed as

cancer disparitiescancer screeningcervical cancercolposcopyhuman papillomavirus (HPV)

Identifiers

PMID38516651
PMCPMC10956530

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.