Evidence map›Paper›PMID 38516277›Full record

ArticlePNAS nexus2024

Yoshitaka Fujihara, Haruhiko Miyata, Ferheen Abbasi, Tamara Larasati, Kaori Nozawa, Zhifeng Yu, Masahito Ikawa, Martin M Matzuk

Open access · goldAbstract read
In one paragraph

Article in PNAS nexus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Testis expressed 50 is essential for maintaining sperm acrosome integrity during epididymal transit.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yoshitaka FujiharaDepartment of Advanced Medical Technologies, National Cerebral and Cardiovascular Center, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0000-0001-8332-3507
Haruhiko MiyataResearch Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.ORCID https://orcid.org/0000-0003-4758-5803
Ferheen AbbasiResearch Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
Tamara LarasatiResearch Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
Kaori NozawaDepartment of Advanced Medical Technologies, National Cerebral and Cardiovascular Center, Suita, Osaka 564-8565, Japan.
Zhifeng YuCenter for Drug Discovery, Baylor College of Medicine, Houston, TX 77030, USA.
Masahito IkawaResearch Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.ORCID https://orcid.org/0000-0001-9859-6217
Martin M MatzukCenter for Drug Discovery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID https://orcid.org/0000-0002-1445-8632
Baylor College of Medicine · USThe University of Osaka · JPThe University of Tokyo · JPUniversity of California, Davis · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Targeting sperm-specific proteins during meiosis and sperm morphogenesisP01HD087157 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI GARCIA, THOMAS · 2017 to 2021
$6.2M
Functional analysis of novel testis-expressed secreted and transmembrane proteinsR01HD088412 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MARTIN M. MATZUK · 2016 to 2026
$4.5M
NCI NIH HHS P30 CA125123NICHD NIH HHS P01 HD087157NICHD NIH HHS R01 HD088412
6 · The paper itself

Abstract

Each year, infertility affects 15% of couples worldwide, with 50% of cases attributed to men. It is assumed that sperm head shape is important for sperm-zona pellucida (ZP) penetration but research has yet to elucidate why. We generated testis expressed 46 (

Indexed as

CRISPR-Cas9fertilizationinfertilityspermatogenesiszona pellucida

Identifiers

PMID38516277
PMCPMC10957234
OpenAlexW4392704562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.