Evidence map›Paper›PMID 38516245›Full record

SynthesisWorld journal of gastroenterology2024

Prevalence and clinical impact of sarcopenia in liver transplant recipients: A meta-analysis.

Min-Jie Jiang, Mu-Chen Wu, Zhong-Hui Duan, Jing Wu, Xiao-Tong Xu, Juan Li, Qing-Hua Meng

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Min-Jie JiangDepartment of Hepatology, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Mu-Chen WuDepartment of Hepatology, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Zhong-Hui DuanDepartment of Emergency, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Jing WuDepartment of Hepatology, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Xiao-Tong XuDepartment of Hepatology, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Juan LiDepartment of Hepatology, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
Qing-Hua MengDepartment of Hepatology, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China. meng_qh0805@ccmu.edu.cn.
Capital Medical University · CNBeijing YouAn Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of sarcopenia in patients undergoing liver transplantation (LT) remains to be determined partly because of different diagnostic criteria. Sarcopenia has recently been recognized as a new prognostic factor for predicting outcomes in LT candidates.

aimTo estimate the prevalence of sarcopenia and evaluate its clinical effect on LT candidates.

methodsThis systematic search was conducted in PubMed, Web of Science, Embase, and Cochrane Library for original English-language articles that investigated the prevalence and influence of sarcopenia in patients undergoing LT from database inception to November 30, 2022. Cohort studies of the definition of sarcopenia that estimate sarcopenia prevalence and evaluate its effect on clinical outcomes and the risk of mortality were included.

resultsTwenty-five studies involving 7760 patients undergoing LT were included. The pooled prevalence of sarcopenia in patients undergoing LT was 40.7% [95% confidence intervals (95%CI): 32.1-49.6]. The 1-, 3-, and 5-year cumulative probabilities of post-LT survival in patients with preoperative sarcopenia were all lower than those without sarcopenia (

conclusionSarcopenia is prevalent in a substantial proportion of patients undergoing LT and is strongly and independently associated with higher a risk of mortality risk.

Indexed as

Liver TransplantationPostoperative ComplicationsSarcopeniaHumansLength of StayPreoperative PeriodPrevalencePrognosisRisk FactorsTransplant RecipientsClinical outcomesLiver transplantationMortalitySarcopenia

Identifiers

PMID38516245
PMCPMC10950632
OpenAlexW4392179289

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.