Evidence map›Paper›PMID 38516085›Full record

ArticleChemical science2024

Controlled node growth on the surface of polymersomes.

Marjolaine Thomas, Spyridon Varlas, Thomas R Wilks, Stephen D P Fielden, Rachel K O'Reilly

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Coronal Complexation Induces Snowman-Shaped Janus Polymersome Formation.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marjolaine ThomasSchool of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK s.fielden@bham.ac.uk r.oreilly@bham.ac.uk.
Spyridon VarlasSchool of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK s.fielden@bham.ac.uk r.oreilly@bham.ac.uk.ORCID https://orcid.org/0000-0002-4171-7572
Thomas R WilksSchool of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK s.fielden@bham.ac.uk r.oreilly@bham.ac.uk.
Stephen D P FieldenSchool of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK s.fielden@bham.ac.uk r.oreilly@bham.ac.uk.ORCID https://orcid.org/0000-0001-7883-8135
Rachel K O'ReillySchool of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK s.fielden@bham.ac.uk r.oreilly@bham.ac.uk.ORCID https://orcid.org/0000-0002-1043-7172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Incorporating nucleobases into synthetic polymers has proven to be a versatile method for controlling self-assembly. The formation of strong directional hydrogen bonds between complementary nucleobases provides a driving force that permits access to complex particle morphologies. Here, nucleobase pairing was used to direct the formation and lengthening of nodes on the outer surface of vesicles formed from polymers (polymersomes) functionalised with adenine in their membrane-forming domains. Insertion of a self-assembling short diblock copolymer containing thymine into the polymersome membranes caused an increase in steric crowding at the hydrophilic/hydrophobic interface, which was relieved by initial node formation and subsequent growth. Nano-objects were imaged by (cryo-)TEM, which permitted quantification of node coverage and length. The ability to control node growth on the surface of polymersomes provides a new platform to develop higher-order nanomaterials with tailorable properties.

Identifiers

PMID38516085
PMCPMC10952076

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.