Evidence map›Paper›PMID 38515990›Full record

ArticleNeurology. Genetics2024

Globus Pallidus Lesion With Iron Deposition and Dopaminergic Denervation in a Patient With a Pathogenic

Victoire Leclert, Chloe Laurencin, Roxana Ameli, Marc Hermier, Anthime Flaus, Stephane Prange, Gaetan Lesca, Stephane Thobois

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Victoire LeclertFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.
Chloe LaurencinFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.ORCID https://orcid.org/0000-0002-1516-5401
Roxana AmeliFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.
Marc HermierFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.ORCID https://orcid.org/0000-0002-4461-2346
Anthime FlausFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.ORCID https://orcid.org/0000-0001-5877-2159
Stephane PrangeFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.ORCID https://orcid.org/0000-0002-0812-7634
Gaetan LescaFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.ORCID https://orcid.org/0000-0001-7691-9492
Stephane ThoboisFrom the Department of Neurology C (V.L., C.L., S.P., S.T.), Expert Parkinson Center NS-PARK/FCRIN, Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital, Bron; Lyon Neuroscience Research Center (C.L., A.F.), UMR5292, INSERM U1028/CNRS; Department of Neuroradiology (R.A., M.H.); Nuclear Medicine Department (A.F.), Hospices Civils de Lyon, Pierre Wertheimer Neurological Hospital; Marc Jeannerod Cognitive Neuroscience Institute (S.P., S.T.), CNRS, UMR 5229, Bron; Faculté de Médecine et Maïeutique Lyon Sud Charles-Mérieux (S.P., G.L., S.T.), Université de Lyon, Université Claude-Bernard Lyon I; Department of Genetics (G.L.), Hospices Civils de Lyon, Mother Child Hospital, Bron; and Physiopathology and Genetics of Neurons and Muscles (G.L.), UMR5261, U1315, Institut NeuroMyoGène, Lyon, France.ORCID https://orcid.org/0000-0002-9639-6702
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Methods: A 26-year-old female patient with intellectual disability, behavioral, and psychiatric disorders treated by neuroleptics for many years developed a parkinsonian syndrome associated with mild hand dystonia and chorea. A 3T brain MRI and I Results: MRI of the brain found bilateral pallidal lesions consistent with neurodegeneration with iron accumulation. The I Discussion: This is a description of dopaminergic denervation and globus pallidus lesions with iron accumulation related to a

Identifiers

PMID38515990
PMCPMC10955334
OpenAlexW4392938444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.