Evidence map›Paper›PMID 38515988›Full record

SynthesisFrontiers in medicine2024

Antimicrobial treatment in invasive infections caused by

Radica Zivkovic Zaric, Petar Canovic, Milan Zaric, Marko Vuleta, Katarina Vuleta Nedic, Jovan Jovanovic, Nenad Zornic, Jelena Nesic, Marko Spasic, Stefan Jakovljevic and 6 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. IDCases · 2026
    Article
  3. Rare Bloodstream Infection ofInfection and drug resistance · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Radica Zivkovic ZaricDepartment of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Petar CanovicDepartment of Biochemistry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Milan ZaricDepartment of Biochemistry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Marko VuletaDepartment of Cardiology, General Hospital Dragisa Misovic, Belgrade, Serbia.
Katarina Vuleta NedicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Jovan JovanovicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Nenad ZornicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Jelena NesicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Marko SpasicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Stefan JakovljevicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Milena IlicDepartment of Pathology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Dalibor JovanovicDepartment of Pathology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Zeljko TodorovicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Petar ArsenijevicUniversity Clinical Center Kragujevac, Kragujevac, Serbia.
Miroslav SovrlicFaculty of Medical Sciences, Center for Harm Reduction of Biological and Chemical Hazards, University of Kragujevac, Kragujevac, Serbia.
Jasmina MilovanovicDepartment of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Corynebacterium, Nocardia, Rhodococcus, Mycobacterium, as well as Gordonia genera belongs to the genus Gordonia, Actinomycetia class. Methods: We have registered this systematic review in PROSPERO database of systematic reviews and meta-analyses with the number CRD42022369974. Results: A total of 24 publications were included (22 case reports and two case series) with 28 individual cases. The oldest patients had 92 years, and the youngest patients had 13 years. Clinical signs of infection were present in six patients (21%). All isolates were susceptible to ciprofloxacin, imipenem, and amikacin. Vancomycin was the most frequently used antibiotic with nine cases followed by ciprofloxacin, ceftriaxone, and amoxicillin/clavulanic acid. Conclusion: Although there are no standardized recommendations to date, successful treatment with a favorable outcome has most often been carried out with fluoroquinolones, vancomycin with or without aminoglycosides, as well as carbapenems.

Indexed as

antimicrobial treatmentciprofloxacinGordonia bronchialisinvasive infectionsvancomycin

Identifiers

PMID38515988
PMCPMC10957228

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.