Evidence map›Paper›PMID 38515777›Full record

ReviewMedical review (2021)2024

Nanotechnology-based delivery systems to overcome drug resistance in cancer.

Harsh Patel, Jiaxin Li, Letao Bo, Riddhi Mehta, Charles R Ashby, Shanzhi Wang, Wei Cai, Zhe-Sheng Chen

Abstract readReview
In one paragraph

Review in Medical review (2021), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Biofabrication ofLife (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Harsh PatelCollege of Pharmacy and Health Sciences, St. John's University, New York, NY, USA.ORCID https://orcid.org/0000-0002-3416-8931
Jiaxin LiCollege of Pharmacy and Health Sciences, St. John's University, New York, NY, USA.
Letao BoCollege of Pharmacy and Health Sciences, St. John's University, New York, NY, USA.
Riddhi MehtaSt. John's College of Liberal Arts and Sciences, St. John's University, New York, NY, USA.
Charles R AshbyCollege of Pharmacy and Health Sciences, St. John's University, New York, NY, USA.
Shanzhi WangCollege of Pharmacy and Health Sciences, St. John's University, New York, NY, USA.
Wei CaiSchool of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, Hunan Province, China.ORCID https://orcid.org/0000-0002-8849-0280
Zhe-Sheng ChenCollege of Pharmacy and Health Sciences, St. John's University, New York, NY, USA.ORCID https://orcid.org/0000-0002-8289-097X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer nanomedicine is defined as the application of nanotechnology and nanomaterials for the formulation of cancer therapeutics that can overcome the impediments and restrictions of traditional chemotherapeutics. Multidrug resistance (MDR) in cancer cells can be defined as a decrease or abrogation in the efficacy of anticancer drugs that have different molecular structures and mechanisms of action and is one of the primary causes of therapeutic failure. There have been successes in the development of cancer nanomedicine to overcome MDR; however, relatively few of these formulations have been approved by the United States Food and Drug Administration for the treatment of cancer. This is primarily due to the paucity of knowledge about nanotechnology and the fundamental biology of cancer cells. Here, we discuss the advances, types of nanomedicines, and the challenges regarding the translation of

Indexed as

drug delivery systemsenhanced permeability and retention effectmultidrug resistancenanoformulationsnanotechnology

Identifiers

PMID38515777
PMCPMC10954245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.