Evidence map›Paper›PMID 38515752›Full record

ArticleFrontiers in immunology2024

VapC12 ribonuclease toxin modulates host immune response during

Shaifali Tyagi, Srikanth Sadhu, Taruna Sharma, Abhijit Paul, Manitosh Pandey, Vaibhav Kumar Nain, Deepak Kumar Rathore, Samrat Chatterjee, Amit Awasthi, Amit Kumar Pandey

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shaifali TyagiMycobacterial Pathogenesis Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Srikanth SadhuImmunobiology Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Taruna SharmaMycobacterial Pathogenesis Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Abhijit PaulComplex Analysis Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Manitosh PandeyMycobacterial Pathogenesis Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Vaibhav Kumar NainMycobacterial Pathogenesis Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Deepak Kumar RathoreImmunobiology Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Samrat ChatterjeeComplex Analysis Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Amit AwasthiImmunobiology Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Amit Kumar PandeyMycobacterial Pathogenesis Laboratory, Translational Health Science and Technology Institute, Faridabad, Haryana, India.
Translational Health Science and Technology Institute · INJawaharlal Nehru University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanistic understanding of antibiotic persistence is a prerequisite in controlling the emergence of MDR cases in Tuberculosis (TB). We have reported that the cholesterol-induced activation of VapC12 ribonuclease is critical for disease persistence in TB. In this study, we observed that relative to the wild type, mice infected with Δ

Indexed as

Mycobacterium tuberculosisRibonucleasesTuberculosisAnimalsImmunity, InnateMicePhenotypeToxins, BiologicalRibonucleasesToxins, Biologicaland inflammationneutrophilspersistencetoxin-antitoxintuberculosisvirulence

Identifiers

PMID38515752
PMCPMC10955575
OpenAlexW4392561014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.