Evidence map›Paper›PMID 38515749›Full record

ReviewFrontiers in immunology2024

ROS signaling in innate immunity via oxidative protein modifications.

Renuka Ramalingam Manoharan, Ankush Prasad, Pavel Pospíšil, Julia Kzhyshkowska

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
23.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 97 citations in OpenAlex.

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  10. Polyphenol-Loaded Liposomal Nanocarriers fromMolecules (Basel, Switzerland) · 2026
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Renuka Ramalingam ManoharanDepartment of Biophysics, Faculty of Science, Palacký University, Olomouc, Czechia.
Ankush PrasadDepartment of Biophysics, Faculty of Science, Palacký University, Olomouc, Czechia.
Pavel PospíšilDepartment of Biophysics, Faculty of Science, Palacký University, Olomouc, Czechia.
Julia KzhyshkowskaInstitute of Transfusion Medicine and Immunology, Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Palacký University Olomouc · CZGerman Red Cross · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The innate immune response represents the first-line of defense against invading pathogens. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated in various aspects of innate immune function, which involves respiratory bursts and inflammasome activation. These reactive species widely distributed within the cellular environment are short-lived intermediates that play a vital role in cellular signaling and proliferation and are likely to depend on their subcellular site of formation. NADPH oxidase complex of phagocytes is known to generate superoxide anion radical (O

Indexed as

Hydrogen PeroxideSuperoxidesHypochlorous AcidImmunity, InnateOxidation-ReductionOxidative StressHydrogen PeroxideHypochlorous AcidSuperoxidesinflammationinnate immune responsemacrophageneutrophilsoxidative stressprotein oxidationreactive oxygen species

Identifiers

PMID38515749
PMCPMC10954773
OpenAlexW4392559080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.