Evidence map›Paper›PMID 38515575›Full record

SynthesisFrontiers in oncology2024

A systematic review of primary large cell neuroendocrine carcinoma of the prostate.

Ngan Nguyen, Ronald Dean Franz, Omar Mohammed, Richard Huynh, Christine Kim Son, Rida Nusrat Khan, Bilawal Ahmed

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Neuroendocrine differentiation in prostate neoplasms.Pathologie (Heidelberg, Germany) · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ngan NguyenHematology and Medical Oncology, The Oncology Institute of Hope and Innovation, Riverside, CA, United States.
Ronald Dean FranzCollege of Medicine, The University of Tennessee Health Science Center (UTHSC), Memphis, TN, United States.
Omar MohammedDepartment of Hematology and Oncology, The University of Tennessee Health Science Center (UTHSC), Memphis, TN, United States.
Richard HuynhDepartment of Internal Medicine, The University of Tennessee Health Science Center (UTHSC), Memphis, TN, United States.
Christine Kim SonDepartment of Hematology and Oncology, The University of Tennessee Health Science Center (UTHSC), Memphis, TN, United States.
Rida Nusrat KhanCollege of Medicine, The University of Tennessee Health Science Center (UTHSC), Memphis, TN, United States.
Bilawal AhmedDepartment of Hematology and Oncology, The University of Tennessee Health Science Center (UTHSC), Memphis, TN, United States.
University of Tennessee Health Science Center · USOncology Institute of Hope and Innovation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Large cell neuroendocrine carcinoma (LCNEC) is a rare subtype of prostate cancer. The pathogenesis, clinical manifestation, treatment options, and prognosis are uncertain and underreported. Materials and methods: A systematic search was conducted in April 2022 through PubMed, Embase, and Cochrane. We reviewed cases of LCNEC developed either from Results: A total of 25 patients with a mean age of 70.4 (range 43 87 years old) from 18 studies were included in this review. 13 patients were diagnosed with Conclusion: LCNEC of the prostate is a rare disease that can occur

Indexed as

adenocarcinomagenitourinary cancerlarge cell neuroendocrine carcinomaneuroendocrine cancerprostate cancerprostate specific antigensystematic review

Identifiers

PMID38515575
PMCPMC10955467
OpenAlexW4392561108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.