Evidence map›Paper›PMID 38515113›Full record

ArticleParasites & vectors2024

The genetic diversity of Oncomelania hupensis robertsoni, intermediate hosts of Schistosoma japonicum in hilly regions of China, using microsatellite markers.

Jing Song, Hongqiong Wang, Shizhu Li, Chunhong Du, Peijun Qian, Wenya Wang, Meifen Shen, Zongya Zhang, Jihua Zhou, Yun Zhang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Jing Song *Department of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China.
Hongqiong Wang *Department of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China.
Shizhu LiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Tropical Diseases Research; NHC Key Laboratory of Parasite and Vector Biology; WHO Collaborating Center for Tropical Diseases; National Center for International Research on Tropical Diseases, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention, Shanghai, 200025, China.
Chunhong DuDepartment of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China.
Peijun QianNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Tropical Diseases Research; NHC Key Laboratory of Parasite and Vector Biology; WHO Collaborating Center for Tropical Diseases; National Center for International Research on Tropical Diseases, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention, Shanghai, 200025, China.
Wenya WangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Tropical Diseases Research; NHC Key Laboratory of Parasite and Vector Biology; WHO Collaborating Center for Tropical Diseases; National Center for International Research on Tropical Diseases, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention, Shanghai, 200025, China.
Meifen ShenDepartment of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China.
Zongya ZhangDepartment of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China.
Jihua ZhouDepartment of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China.
Yun ZhangDepartment of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China.
Chunying LiSchool of Public Health, Kunming Medical University, Kunming, 650500, China.
Yuwan HaoNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Tropical Diseases Research; NHC Key Laboratory of Parasite and Vector Biology; WHO Collaborating Center for Tropical Diseases; National Center for International Research on Tropical Diseases, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention, Shanghai, 200025, China. haoyw@nipd.chinacdc.cn.
Yi DongDepartment of Schistosomiasis Control and Prevention, Yunnan Institute of Endemic Disease Control and Prevention, Dali, 671000, China. dydali@sina.com.
Yunnan Center for Disease Control And Prevention · CNHospital for Tropical Diseases · VNKunming Medical University · CNShanghai Jiao Tong University · CNVector (United States) · USYunnan Institute of Endemic Diseases Control and Prevention · CN

Funding

Dali Prefecture Science and Technology Plan Project D2022ZA0115National Key Research and Development Program of China No. 2021YFC2300800, 2021YFC2300803Open project of Key Laboratory of Parasite and Vector Biology of National Health Commission NHCKFKT2023-08Project supported by the National Parasite Resource Bank 2019-194-30Youth Science and Technology Talent Training Project of Yunnan Institute of Endemic Disease Control and Prevention YIEDC-G202101Youth Science and Technology Talent Training Project of Yunnan Institute of Endemic Disease Control and Prevention YIEDC-G202102
6 · The paper itself

Abstract

backgroundThe elimination of schistosomiasis remains a challenging task, with current measures primarily focused on the monitoring and control of Oncomelania hupensis (O. hupensis) snail, the sole intermediate host of Schistosome japonicum. Given the emerging, re-emerging, and persistent habitats of snails, understanding their genetic diversity might be essential for their successful monitoring and control. The aims of this study were to analyze the genetic diversity of Oncomelania hupensis robertsoni (O. h. robertsoni) using microsatellite DNA markers; and validate the applicability of previously identified microsatellite loci for O. hupensis in hilly regions.

methodsA total of 17 populations of O. h. robertsoni from Yunnan Province in China were selected for analysis of genetic diversity using six microsatellite DNA polymorphic loci (P82, P84, T4-22, T5-11, T5-13, and T6-27).

resultsThe number of alleles among populations ranged from 0 to 19, with an average of 5. The average ranges of expected (He) and observed (Ho) heterozygosity within populations were 0.506 to 0.761 and 0.443 to 0.792, respectively. The average fixation index within the population ranged from - 0.801 to 0.211. The average polymorphic information content (PIC) within the population ranged from 0.411 to 0.757, appearing to be polymorphic for all loci (all PIC > 0.5), except for P28 and P48. A total of 68 loci showed significant deviations from Hardy-Weinberg equilibrium (P < 0.05), and pairwise Fst values ranged from 0.051 to 0.379. The analysis of molecular variance indicated that 88% of the variation occurred within snail populations, whereas 12% occurred among snail populations. Phylogenetic trees and principal coordinate analysis revealed two distinct clusters within the snail population, corresponding to "Yunnan North" and "Yunnan South".

conclusionsO. h. robertsoni exhibited a relatively high level of genetic differentiation, with variation chiefly existing within snail populations. All snail in this region could be separated into two clusters. The microsatellite loci P82 and P84 might not be suitable for classification studies of O. hupensis in hilly regions. These findings provided important information for the monitoring and control of snail, and for further genetic diversity studies on snail populations.

Indexed as

GastropodaSchistosoma japonicumAnimalsChinaDNAGenetic VariationMicrosatellite RepeatsPhylogenyDNAGenetic diversityMicrosatellite DNAOncomelania hupensisOncomelania hupensis robertsoniSchistosome japonicum

Identifiers

PMID38515113
PMCPMC10956175
OpenAlexW4393051275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.