Evidence map›Paper›PMID 38515108›Full record

ArticleBMC urology2024

Optimizing targeting strategies for lithotripsy through in-vitro and in vivo studies with consideration of respiratory regularity.

Sung Yong Cho, Hyeji Park, Jae Suk Park, Seong Chan Kim, Oh Bin Kwon, Hyun Jae Song, Min Joo Choi

Abstract read
In one paragraph

Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sung Yong ChoDepartment of Urology, Seoul National University Hospital, Seoul, Korea.
Hyeji ParkDepartment of Urology, Seoul National University Hospital, Seoul, Korea.
Jae Suk ParkDepartment of Urology, Seoul National University Hospital, Seoul, Korea.
Seong Chan KimInterdisciplinary Postgraduate Program in Biomedical Engineering, Jeju National University, Jeju, Korea.
Oh Bin KwonInterdisciplinary Postgraduate Program in Biomedical Engineering, Jeju National University, Jeju, Korea.
Hyun Jae SongDepartment of Electronic Engineering, Sogang University, Seoul, Korea.
Min Joo ChoiInterdisciplinary Postgraduate Program in Biomedical Engineering, Jeju National University, Jeju, Korea. hifuchoi@gmail.com.

Funding

Funding: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) and the Korea Medical Device Development Fund grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, the Ministry of Food and Drug Safety) (No. 2022R1F1A1059835), (Project Number: 1711194216, RS-2020-KD000010)Korea Medical Device Development Fund grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, the Ministry of Food and Drug Safety) 1711194216, RS-2020-KD000010
6 · The paper itself

Abstract

backgroundThis work aimed to identify a method to achieve improved stone targeting and safety in shockwave lithotripsy by accounting for respiration.

methodsWe set up an electromotive device simulating renal movement during respiration to place artificial stones within the phantom gel, measuring stone weight changes before and after shockwave exposure and the cavitation damage. We conducted clinical trials using respiratory masks and sensors to monitor and analyze patient respiration during shockwave lithotripsy.

resultsThe in vitro efficiency of lithotripsy was higher when adjusted for respiration than when respiration was not adjusted for. Slow respiration showed the best efficiency with higher hit rates when not adjusted for respiration. Cavitation damage was also lowest during slow respiration. The clinical study included 52 patients. Respiratory regularity was maintained above 90% in regular respiration. When respiration was regular, the lithotripsy rate was about 65.6%, which stayed at about 40% when respiration was irregular. During the lithotripsy, the participants experienced various events, such as sleep, taking off their masks, talking, movement, coughing, pain, nervousness, and hyperventilation. The generation of shockwaves based on respiratory regularity could reduce pain in patients.

conclusionThese results suggest a more accurate lithotripsy should be performed according to respiratory regularity.

Indexed as

Kidney CalculiLithotripsyHumansKidneyPainPhantoms, ImagingResearch DesignTreatment OutcomeExtracorporeal shockwave therapyLithotripsyRespirationRespiratory regularityTreatment outcome

Identifiers

PMID38515108
PMCPMC10958973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.