SynthesisBMC cancer2024
The association between organised colorectal cancer screening strategies and reduction of its related mortality: a systematic review and meta-analysis.
Synthesis in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global colorectal cancer screening programs and coverage rate estimation: an evidence synthesis.Journal of translational medicine · 2025Pooled it
- Global burden and trends of stomach cancer, Colon and rectum cancer, peptic ulcer disease, and gastritis and duodenitis from 1990 to 2021: a systematic analysis for the global burden of disease study 2021.Future science OA · 2026Article
- When Patients Have No Ride Home: Addressing Transportation Barriers That Exacerbate Disparities in Access to Timely Diagnostic Colonoscopies.Journal of general internal medicine · 2026Article
- Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management.MedComm · 2026Review
- Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours.The Journal of pathology · 2026Review
- Mailed faecal immunochemical test programmes and educational inequalities in colorectal cancer screening in Europe: a difference-in-differences analysis.International journal of epidemiology · 2026Article
- Fecal Immunochemical Test Screening Status, Stage Distribution, and Overall Survival in Colorectal Cancer: A Propensity Score-Matched Cohort Study from a Regional Hospital in Taiwan.Diagnostics (Basel, Switzerland) · 2026Article
- Organised Colorectal Cancer Screening and Changes in Mortality and Incidence Trends: A Population-Based Study.Cancers · 2026Article
- Optimizing colorectal cancer screening through polygenic risk score-based risk stratification: evidence from a population-based cohort and screening trial.Genome medicine · 2026Article
- Reliable classification of polyps based on artificial intelligence: a development and validation study.EClinicalMedicine · 2026Article
- Projections of colorectal cancer mortality to 2040 in Mexico and their association with socioeconomic status.Cancer causes & control : CCC · 2026Observational
- Ginsenoside Rh1 inhibits tumor growth in mice with colorectal cancer and depressive symptoms via modulation of the gut microbiota and tumor microenvironment.Molecular medicine reports · 2025Article
- Limited Diagnostic Yield of Routine Gastroscopy in FIT-Positive Patients.Diagnostics (Basel, Switzerland) · 2025Article
- The Relationship Between the Health Literacy Levels of Women of Reproductive Age and Their Level of Knowledge About Cancer Screenings.Journal of evaluation in clinical practice · 2025Article
- Risk factors, prevention and screening of colorectal cancer: A rising problem.World journal of gastroenterology · 2025Review
- Organized Colorectal Cancer Screening Programs in Switzerland - Quo Vadis?International journal of public health · 2025Article
- Global, regional and national burden of colorectal cancer and its risk factors, 1990-2021: a systematic analysis for the GBD 2021.Frontiers in oncology · 2025Article
- Article
- Surgical Emergencies in Rectal Cancer: A Narrative Review.Journal of clinical medicine · 2024Review
- Machine learning-based model for CD4Scientific reports · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess the long-term association between organised colorectal cancer (CRC) screening strategies and CRC-relate mortality.
methodsWe systematically reviewed studies on organised CRC screening through PubMed, Ovid Medline, Embase and Cochrane from the inception. We retrieved characteristics of organised CRC screening from included literature and matched mortality (over 50 years) of those areas from the International Agency for Research on Cancer in May 2023. The variations of mortality were reported via the age-standardised mortality ratio. A random-effects model was used to synthesis results.
resultsWe summarised 58 organised CRC screening programmes and recorded > 2.7 million CRC-related deaths from 22 countries where rollout screening programmes were performed. The CRC screening strategy with faecal tests (guaiac faecal occult blood test (gFOBT) or faecal immunochemical tests (FIT)) or colonoscopy as the primary screening offer was associated with a 41.8% reduction in mortality, which was higher than those offered gFOBT (4.4%), FIT (16.7%), gFOBT or FIT (16.2%), and faecal tests (gFOBT or FIT) or flexible sigmoidoscopy (16.7%) as primary screening test. The longer duration of screening was associated with a higher reduction in the pooled age-standardised mortality ratio. In particular, the pooled age-standardised mortality ratio became non-significant when the screening of FIT was implemented for less than 5 years.
conclusionsA CRC screening programme running for > 5 years was associated with a reduction of CRC-related mortality. Countries with a heavy burden of CRC should implement sustainable, organised screening providing a choice between faecal tests and colonoscopy as a preferred primary test.
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