Evidence map›Paper›PMID 38514646›Full record

ArticleScientific reports2024

Phototoxicity of low doses of light and influence of the spectral composition on human RPE cells.

Anaïs Françon, Kimberley Delaunay, Thara Jaworski, Cécile Lebon, Emilie Picard, Jenny Youale, Francine Behar-Cohen, Alicia Torriglia

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Photooxidative molecular damage under blue light.Experimental & molecular medicine · 2026
    Review
  2. Article
  3. Article
  4. Photosensitivity of an aging brain.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anaïs FrançonCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France.
Kimberley DelaunayCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France.
Thara JaworskiCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France.
Cécile LebonCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France.
Emilie PicardCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France.
Jenny YoualeCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France.
Francine Behar-CohenCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France.
Alicia TorrigliaCentre de Recherche Des Cordeliers, INSERM UMRS 1138, Université Paris Cité, Sorbonne Université. Team: Physiopathology of Ocular Diseases: Therapeutic Innovations, 15, Rue de L'école de Médecine, 75006, Paris, France. Alicia.torriglia@inserm.fr.
Inserm · FR

Funding

Agence Nationale de la Recherche AAPG2020/CE18Agence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail 2022/EST/134
6 · The paper itself

Abstract

Light is known to induce retinal damage affecting photoreceptors and retinal pigment epithelium. For polychromatic light, the blue part of the spectrum is thought to be the only responsible for photochemical damage, leading to the establishment of a phototoxicity threshold for blue light (445 nm). For humans it corresponds to a retinal dose of 22 J/cm

Indexed as

Induced Pluripotent Stem CellsRetinal Pigment EpitheliumAnimalsHumansPrimatesRetina

Identifiers

PMID38514646
PMCPMC10957882
OpenAlexW4393063259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.