Evidence map›Paper›PMID 38514520›Full record

ArticleGeroScience2024

Age-related decline in cognitive flexibility and inadequate preparation: evidence from task-state network analysis.

Haishuo Xia, Ting Li, Yongqing Hou, Zijin Liu, Antao Chen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GeroScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Haishuo Xia *Faculty of Psychology, Southwest University, Chongqing, China.
Ting Li *Faculty of Psychology, Beijing Normal University, Beijing, China.
Yongqing HouFaculty of Psychology, Southwest University, Chongqing, China.
Zijin LiuSchool of Psychology, Shanghai University of Sport, Shanghai, 200438, China.
Antao ChenSchool of Psychology, Shanghai University of Sport, Shanghai, 200438, China. chenantao@sus.edu.cn.ORCID 0000-0001-9321-681X
Shanghai University of Sport · CNSouthwest University · CNBeijing Normal University · CN

Funding

National Natural Science Foundation of China 32371105
6 · The paper itself

Abstract

Behavioral evidence showed decreased cognitive flexibility in older adults. However, task-based network mechanisms of cognitive flexibility in aging (CFA) remain unclear. Here, we provided the first task-state network evidence that CFA was associated with inadequate preparation for switching trials by revealing age-related changes in functional integration. We examined functional integration in a letter-number switch task that distinguished between the cue and target stages. Both young and older adults showed decreased functional integration from the cue stage to the target stage, indicating that control-related processes were executed as the task progressed. However, compared to young adults, older adults showed less cue-to-target reduction in functional integration, which was primarily driven by higher network integration in the target stage. Moreover, less cue-to-target reductions were correlated with age-related decreases in task performance in the switch task. To sum up, compared to young adults, older adults pre-executed less control-related processes in the cue stage and more control-related processes in the target stage. Therefore, the decline in cognitive flexibility in older adults was associated with inadequate preparation for the impending demands of cognitive switching. This study offered novel insights into network mechanisms underlying CFA. Furthermore, we highlighted that training the function of brain networks, in conjunction with providing more preparation time for older adults, may be beneficial to their cognitive flexibility.

Indexed as

AgingAdultAgedCognitionCognitive DysfunctionCuesExecutive FunctionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsTask Performance and AnalysisYoung AdultAgingCognitive flexibilityFunctional integrationFunctional network

Identifiers

PMID38514520
PMCPMC11493936
OpenAlexW4393067748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.