Evidence map›Paper›PMID 38514398›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2024

Dielectric elastomer actuator-based valveless pump as Fontan failure assist device: introduction and preliminary study.

Amine Benouhiba, Armando Walter, Silje Ekroll Jahren, Thomas Martinez, Francesco Clavica, Paul Philipp Heinisch, Dominik Obrist, Yoan Civet, Yves Perriard

Open access · diamondAbstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Amine BenouhibaIntegrated Actuators Laboratory (LAI), École polytechnique fédérale de Lausanne (EPFL), Neuchâtel, Switzerland.ORCID 0000-0002-9244-1190
Armando WalterIntegrated Actuators Laboratory (LAI), École polytechnique fédérale de Lausanne (EPFL), Neuchâtel, Switzerland.ORCID 0000-0002-9812-8525
Silje Ekroll JahrenIntegrated Actuators Laboratory (LAI), École polytechnique fédérale de Lausanne (EPFL), Neuchâtel, Switzerland.ORCID 0000-0003-3931-5141
Thomas MartinezIntegrated Actuators Laboratory (LAI), École polytechnique fédérale de Lausanne (EPFL), Neuchâtel, Switzerland.
Francesco ClavicaIntegrated Actuators Laboratory (LAI), École polytechnique fédérale de Lausanne (EPFL), Neuchâtel, Switzerland.ORCID 0000-0002-8967-5877
Paul Philipp HeinischDivision of Congenital and Pediatric Heart Surgery, University Hospital of Munich, Ludwig-Maximilians-University, Munich, Germany.ORCID 0000-0003-4061-4499
Dominik ObristARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.ORCID 0000-0002-6062-9076
Yoan CivetIntegrated Actuators Laboratory (LAI), École polytechnique fédérale de Lausanne (EPFL), Neuchâtel, Switzerland.ORCID 0000-0002-7601-6223
Yves PerriardIntegrated Actuators Laboratory (LAI), École polytechnique fédérale de Lausanne (EPFL), Neuchâtel, Switzerland.ORCID 0000-0003-2350-4562
École Polytechnique Fédérale de Lausanne · CHUniversity of Bern · CHDeutsches Herzzentrum München · DE

Funding

Werner Siemens Foundation
6 · The paper itself

Abstract

objectivesFontan failure refers to a condition in which the Fontan circulation, a surgical procedure used to treat certain congenital heart defects, becomes insufficient, leading to compromised cardiac function and potential complications. This in vitro study therefore investigates the feasibility of bladeless impedance-driven cavopulmonary assist device via dielectric elastomer actuator (DEA) as a means to address Fontan failure.

methodsA cavopulmonary assist device, constructed using DEA technologies and employing the impedance pump concept, is subjected to in vitro testing within a closed-loop setup. This study aims to assess the device's functionality and performance under controlled conditions, providing valuable insights into its potential application as a cavopulmonary assistive technology.

resultsThe DEA-based pump, measuring 50 mm in length and 30 mm in diameter, is capable of achieving substantial flow rates within a closed-loop setup, reaching up to 1.20 l/min at an activation frequency of 4 Hz. It also provides a broad range of working internal pressures (<10 to >20 mmHg). Lastly, the properties of the flow (direction, magnitude, etc.) can be controlled by adjusting the input signal parameters (frequency, amplitude, etc.).

conclusionsIn summary, the results suggest that the valveless impedance-driven pump utilizing DEA technology is promising in the context of cavopulmonary assist devices. Further research and development in this area may lead to innovative and potentially more effective solutions for assisting the right heart, ultimately benefiting patients with heart-related health issues overall, with a particular focus on those experiencing Fontan failure.

Indexed as

Cavopulmonary assist deviceCongenital heart defectFontan failureValveless pumping

Identifiers

PMID38514398
PMCPMC11001492
OpenAlexW4394764190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.