Evidence map›Paper›PMID 38514278›Full record

ReviewPlacenta2024

Beyond 2D: Novel biomaterial approaches for modeling the placenta.

Samantha G Zambuto, Adrienne K Scott, Michelle L Oyen

Abstract readReview
In one paragraph

Review in Placenta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Stem cell models of human embryo implantation and trophoblast invasion.Current opinion in genetics & development · 2025
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samantha G ZambutoDepartment of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO, USA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA; Center for Women's Health Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Adrienne K ScottDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA; Center for Women's Health Engineering, Washington University in St. Louis, St. Louis, MO, USA; Center for Regenerative Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Michelle L OyenDepartment of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO, USA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA; Center for Women's Health Engineering, Washington University in St. Louis, St. Louis, MO, USA; Center for Regenerative Medicine, Washington University in St. Louis, St. Louis, MO, USA. Electronic address: oyen@wustl.edu.

Funding

TRAINING IN REGENERATIVE MEDICINET32EB028092 · NIBIB · WASHINGTON UNIVERSITY · PI Farshid Guilak · 2020 to 2026
$2.0M
Clinical Outcomes Research Training in Female Lower Urinary Tract DisordersT32DK120497 · NIDDK · WASHINGTON UNIVERSITY · PI LOWDER, JERRY LANE, SUTCLIFFE, SIOBHAN · 2020 to 2024
$879k
NIBIB NIH HHS T32 EB028092NIDDK NIH HHS T32 DK120497
6 · The paper itself

Abstract

This review considers fully three-dimensional biomaterial environments of varying complexity as these pertain to research on the placenta. The developments in placental cell sources are first considered, along with the corresponding maternal cells with which the trophoblast interact. We consider biomaterial sources, including hybrid and composite biomaterials. Properties and characterization of biomaterials are discussed in the context of material design for specific placental applications. The development of increasingly complicated three-dimensional structures includes examples of advanced fabrication methods such as microfluidic device fabrication and 3D bioprinting, as utilized in a placenta context. The review finishes with a discussion of the potential for in vitro, three-dimensional placenta research to address health disparities and sexual dimorphism, especially in light of the exciting recent changes in the regulatory environment for in vitro devices.

Indexed as

Biocompatible MaterialsPlacentaAnimalsBioprintingFemaleHumansModels, BiologicalPregnancyPrinting, Three-DimensionalBiocompatible MaterialsBiomaterialsPlacentaThree-dimensional culture

Identifiers

PMID38514278
PMCPMC11399328

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.