Evidence map›Paper›PMID 38514268›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2024

[Research progress on the role of hepatitis B virus DNA integration in chronic hepatitis B].

Y M Chen, J Liu, C W Zhu, L Zhu

Open access · greenAbstract readReviewEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Y M ChenDepartment of Liver Diseases, Infectious Diseases Hospital, Soochow University, Suzhou 215131, China Suzhou Medical College, Soochow University, Suzhou 215131, China.
J LiuDepartment of Infectious Diseases Hospital Affiliated to Soochow University, Suzhou 215131, China.
C W ZhuSuzhou Medical College, Soochow University, Suzhou 215131, China.
L ZhuDepartment of Liver Diseases, Infectious Diseases Hospital, Soochow University, Suzhou 215131, China Suzhou Medical College, Soochow University, Suzhou 215131, China.
Soochow University · CN

Funding

Suzhou City Clinical Key Diseases Diagnosis and Treatment Technology Special Project LCZX202117Suzhou Gusu Health Personnel Training Project GSWS2019068
6 · The paper itself

Abstract

Chronic hepatitis B virus (HBV) infection will greatly contribute to raising the occurrence probability of cirrhosis and hepatocellular carcinoma in patients. Although existing antiviral treatment regimens have a certain effect on delaying disease progression and improving prognosis, it is still not effective in attaining functional cures. Hepatitis B virus DNA integration may be one of the reasons for this phenomenon. Therefore, this paper reviews the possible mechanisms of HBV DNA integration in maintaining chronic inflammation of the liver, evading existing antiviral treatment methods, and inducing hepatocellular carcinoma so as to further deepen the understanding of the role of HBV DNA integration in the occurrence and development of chronic hepatitis B, providing ideas and references for formulating better treatment strategies.

Indexed as

Carcinoma, HepatocellularHepatitis BHepatitis B, ChronicLiver NeoplasmsAntiviral AgentsDNA, ViralHepatitis B virusHumansVirus IntegrationAntiviral AgentsDNA, ViralChronic hepatitis B virus infectionFunctional cureHepatitis B virusIntegrated HBV DNAViral replication

Identifiers

PMID38514268
PMCPMC12850706
OpenAlexW4394739883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.