Evidence map›Paper›PMID 38514168›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2024

Skin-to-skin stabilisation and uninterrupted respiratory support for preterm infants after birth: feasibility of a new and simplified rPAP system.

Sonja Baldursdottir, Kolbrun Gunnarsdottir, Snorri Donaldsson, Baldvin Jonsson, Thomas Drevhammar

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04244890 (Feasibility of Respiratory Management of Infants Needing Positive Pressure Ventilation or CPAP, Using a Single System to Deliver Uninterrupted Support Directly at Birth and the First Hours of Life), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04244890 completednot on this map

Feasibility of Respiratory Management of Infants Needing Positive Pressure Ventilation or CPAP, Using a Single System to Deliver Uninterrupted Support Directly at Birth and the First Hours of Life

TypeobservationalSponsorKarolinska InstitutetRan2020 to 2023Enrolled32ConditionsRespiratory Distress Syndrome, Newborn, Infant, Newborn, Respiratory Insufficiency Syndrome of NewbornArmsUninterrupted CPAP for the first hours of life
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sonja BaldursdottirDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-2264-7449
Kolbrun GunnarsdottirDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden kolbrun.gunnarsdottir@ki.se.ORCID http://orcid.org/0000-0003-2000-2006
Snorri DonaldssonDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-1043-2977
Baldvin JonssonDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-9812-732X
Thomas DrevhammarDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-4038-2221
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rPAP respiratory support system, used for delivery room stabilisation with nasal prongs, has been shown to reduce the need for intubation in extremely preterm infants. A simplified version of the system has been developed. The purpose of this study was to determine the feasibility of providing uninterrupted respiratory support with the simplified rPAP from birth up to 4 hours of life and to assess ease of use for skin-to skin stabilisation.

methodsThis was a non-randomised feasibility study conducted at Karolinska University Hospital, Sweden. Respiratory support with continuous positive airway pressure (CPAP) and positive pressure ventilation if needed was given with the simplified rPAP using heated humidified gases. Respiratory support was provided in the delivery room, during transportation and in the neonatal unit, for a maximum of 4 hours.

results32 preterm infants with a mean (SD) gestational age of 33.4 weeks (±1.2) were included. Of 17 infants born vaginally, 13 were stabilised skin-to-skin. The remaining infants were stabilised on a resuscitation table. All infants received CPAP and nine received positive pressure ventilation. 31 infants received continued support during transport and after arrival in the neonatal unit. Minor interruptions in CPAP support occurred in all infants. The study did not reveal problems with usability of the system.

conclusionIt is feasible to stabilise preterm infants with the simplified respiratory support system both skin-to-skin and on a resuscitation table, and to provide continued respiratory support with the same system during transportation and in the neonatal unit. TRIAL REGISTRATION NUMBER: NCT04244890.

Indexed as

Continuous Positive Airway PressureFeasibility StudiesInfant, PrematureRespiratory Distress Syndrome, NewbornDelivery RoomsFemaleGestational AgeHumansInfant, Extremely PrematureInfant, NewbornKangaroo-Mother Care MethodMaleNon-Randomized Controlled Trials as TopicPositive-Pressure RespirationSwedenNeonatologyRespiratoryResuscitation

Identifiers

PMID38514168
PMCPMC11503089
OpenAlexW4393032668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.