Evidence map›Paper›PMID 38514081›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

Samuel L Cytryn, Neeta Pandit-Taskar, Melissa A Lumish, Steven B Maron, Ping Gu, Geoffrey Y Ku, Joanne F Chou, Marinela Capanu, Ariel Antoine, Diane Loegel and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. PD-L1 PET/CT imaging withEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Challenges in tracer development for tumor microenvironment (TME) imaging.European journal of nuclear medicine and molecular imaging · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. EJNMMI research · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Samuel L CytrynDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Neeta Pandit-TaskarDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Melissa A LumishDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Steven B MaronDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Ping GuDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Geoffrey Y KuDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Joanne F ChouDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Marinela CapanuDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Ariel AntoineDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Diane LoegelDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Lara FederDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Steven PhilemondDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Serge K LyashchenkoDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Jason S LewisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Viktoriya ParoderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Amitabh SrivastavaDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Laura H TangDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Heiko SchoderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Yelena Y JanjigianDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; janjigiy@mskcc.org.
Memorial Sloan Kettering Cancer Center · USCornell University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Anti-programmed death 1 (PD-1) inhibitors are the standard of care for advanced gastroesophageal cancer. Although recommendations and approval by regulatory agencies are often based on programmed death ligand 1 (PD-L1) expression, pathologic assessments of PD-L1 status have several limitations. Single-site biopsies do not adequately capture disease heterogeneity within individual tumor lesions or among several lesions within the same patient, the PD-L1 combined positive score is a dynamic biomarker subject to evolution throughout a patient's disease course, and repeated biopsies are invasive and not always feasible.

Indexed as

B7-H1 AntigenEsophageal NeoplasmsPositron Emission Tomography Computed TomographyStomach NeoplasmsAdultAgedFemaleFluorine RadioisotopesHumansMaleMiddle AgedPilot ProjectsProspective StudiesB7-H1 AntigenCD274 protein, humanFluorine-18Fluorine Radioisotopesesophageal adenocarcinomagastric adenocarcinomaimmunotherapyPD-L1 heterogeneityPD-L1 PET

Identifiers

PMID38514081
PMCPMC11064823
OpenAlexW4393033395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.