Evidence map›Paper›PMID 38513798›Full record

ArticleJournal of vascular surgery. Venous and lymphatic disorders2024

Obese patients with CEAP (clinical, etiology, anatomy, pathophysiology) C2 and C3 disease show enhanced symptom improvement after endovenous thermal ablation.

Zachary R Zottola, Joshua T Geiger, Geena E Choo, Baqir J Kedwai, Mark D Balceniuk, Jennifer L Ellis, Adam J Doyle, Karina A Newhall

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular surgery. Venous and lymphatic disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zachary R ZottolaDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Joshua T GeigerDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Geena E ChooDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Baqir J KedwaiDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Mark D BalceniukDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Jennifer L EllisDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Adam J DoyleDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Karina A NewhallDivision of Vascular Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY. Electronic address: Karina_newhall@urmc.rochester.edu.
University of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndovenous thermal ablation (EVTA) is a prevalent treatment option for patients with severe venous disease. However, the decision to intervene for patients with less severe disease (CEAP [clinical, etiology, anatomy, pathophysiology] C2 and C3) is less clear and becomes further complicated for patients with obesity, a pathology known to increase venous disease symptom severity. Therefore, the objective of this study was to use the Society for Vascular Surgery Vascular Quality Initiative database to evaluate outcomes after EVTA in obese patients with CEAP C2 and C3 venous insufficiency.

methodsUsing the Society for Vascular Surgery Vascular Quality Initiative database, we retrospectively analyzed the initial procedure of all patients with a CEAP clinical class of C2 or C3 who underwent EVTA from January 2015 to December 2021. Patients were grouped by obesity, defined as a body mass index of ≥30 kg/m

resultsThere were 8146 limbs that met the inclusion criteria, of which 5183 (63.6%) were classified as nonobese and 2963 (36.4%) as obese. Obesity showed no impact on improvement in the VCSS (-3.29 vs -3.35; P = .408). Obesity was found to be associated with a larger improvement in overall symptoms, as evidence by a greater improvement in the HASTI score (-7.24 vs -6.62; P < .001). Obese limbs showed a higher incidence of superficial phlebitis (1.5% vs 0.7%; P = .001), but no difference was found in recanalization or any other complication.

conclusionsThese data suggest that obese patients with CEAP clinical class C2 or C3 experience greater improvement in their perceived symptoms after EVTA with little difference in clinical improvement and complications compared with nonobese patients. Although obesity has been associated with increased severity of venous disease symptoms, obese patients are able to derive significant relief after treatment during the short term and may experience greater relief of symptoms than nonobese patients when treated at more mild disease presentations.

Indexed as

Endovascular ProceduresObesitySeverity of Illness IndexVenous InsufficiencyAblation TechniquesAdultAgedDatabases, FactualFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresRecovery of FunctionRetrospective StudiesRisk FactorsLaser therapyObesityPatient-reported outcome measuresRadiofrequency ablationVenous insufficiency

Identifiers

PMID38513798
PMCPMC11523301
OpenAlexW4392947305

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.