Evidence map›Paper›PMID 38513310›Full record

ArticleJournal of geriatric oncology2024

Racial differences in body composition and survival among older adults with gastrointestinal malignancies.

Gabriel F P Aleixo, Daniel L Hess, Mackenzie E Fowler, Smith Giri, Grant R Williams

Open access · greenAbstract read
In one paragraph

Article in Journal of geriatric oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Future of CT body composition research: Methodological discrepancies and advances.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gabriel F P AleixoUniversity of Pennsylvania, Department of Hematology and Oncology, Philadelphia, PA, United States of America. Electronic address: gabriel.aleixo@pennmedicine.upenn.edu.
Daniel L HessThe University of Alabama at Birmingham, Department of Medicine, Birmingham, AL, United States of America.
Mackenzie E FowlerThe University of Alabama at Birmingham, Department of Epidemiology, Birmingham, AL, United States of America.
Smith GiriThe University of Alabama at Birmingham, O'Neal Comprehensive Cancer Center, Birmingham, AL, United States of America.
Grant R WilliamsThe University of Alabama at Birmingham, O'Neal Comprehensive Cancer Center, Birmingham, AL, United States of America.
University of Alabama at Birmingham · USUniversity of Pennsylvania · US

Funding

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults with Colorectal Cancer: The M&M StudyK08CA234225 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, GRANT R · 2018 to 2022
$1.0M
NCI NIH HHS K08 CA234225
6 · The paper itself

Abstract

introductionMuscle and adipose tissue measures can be quantified from routinely obtained computed tomography (CT) images and are predictors of chemotherapy-related toxicities and survival among patients with gastrointestinal (GI) malignancies. Most studies to date have consisted of predominantly White patients, and the role of body composition among minoritized racial groups is unknown. We examined racial differences in body composition and survival among patients with GI malignancies. MATERIALS AND

methodsThis was a prospective cohort study of patients with GI malignancies. Single slices of axial CT images from L3 segments were analyzed using Slice-O-Matic software. The skeletal muscle area (cm

resultsFive hundred forty patients were included, of which 24% were NH-Black. In Cox models stratified by race, each 5 cm DISCUSSION: NH-Black older patients with GI cancers and sarcopenia or myosteatosis have worse overall survival.

Indexed as

Body CompositionGastrointestinal NeoplasmsTomography, X-Ray ComputedAgedAged, 80 and overBlack or African AmericanFemaleHumansMaleMiddle AgedMuscle, SkeletalProportional Hazards ModelsProspective StudiesSarcopeniaWhiteBody compositionGastrointestinal cancerRacial disparitiesSarcopenia

Identifiers

PMID38513310
PMCPMC12493807
OpenAlexW4392974759

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.